Methylene-fatty-acyl-phospholipid synthase

In enzymology, a methylene-fatty-acyl-phospholipid synthase (EC 2.1.1.16) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + phospholipid olefinic fatty acid $\rightleftharpoons$ S-adenosyl-L-homocysteine + phospholipid methylene fatty acid

Thus, the two substrates of this enzyme are S-adenosyl methionine and phospholipid olefinic fatty acid, whereas its two products are S-adenosylhomocysteine and phospholipid methylene fatty acid.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (methenylating). This enzyme is also called unsaturated-phospholipid methyltransferase.

References

• IUBMB entry for 2.1.1.16
• BRENDA references for 2.1.1.16 (Recommended.)
• PubMed references for 2.1.1.16
• PubMed Central references for 2.1.1.16
• Google Scholar references for 2.1.1.16
• Akamatsu Y, Law JH (1970). "Enzymatic alkylenation of phospholipid fatty acid chains by extracts of Mycobacterium phlei". J. Biol. Chem. 245: 701&ndash, 8. PMID 4313604.

External links

The CAS registry number for this enzyme class is 37256-90-9.

• IUBMB entry for 2.1.1.16

• KEGG entry for 2.1.1.16

• BRENDA entry for 2.1.1.16

• NiceZyme view of 2.1.1.16

• EC2PDB: PDB structures for 2.1.1.16

• PRIAM entry for 2.1.1.16

• PUMA2 entry for 2.1.1.16

• IntEnz: Integrated Enzyme entry for 2.1.1.16

• MetaCyc entry for 2.1.1.16

• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0004481: methylene-fatty-acyl-phospholipid synthase

• AMIGO entry for GO code 0004481: methylene-fatty-acyl-phospholipid synthase