Metabolic alkalosis medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Marufa Marium, M.B.B.S[2]
Overview
Supportive therapy for Metabolic alkalosis includes volume repletion, electrolyte repletion, removal of inducing source and after stabilizing patient treatment according to etiology.
Medical Therapy
- Supportive therapy for Metabolic alkalosis includes volume repletion, electrolyte repletion, removal of inducing source and after stabilizing patient treatment according to etiology. Pharmacologic medical therapy is recommended among patients with electrolyte imbalances, hypervolemia, loss of GI hydrogen. Strategies to stabilize patient with metabolic alkalosis includes:
- Hypokalemia/Hypomagnesaemia correction with KCl
- Repletion of volume with normal saline in saline responsive hypovolemic patient
- Acetazolamide, Spironolactone, Amiloride to increase excretion of bicarbonate in hypervolemic patient.
- Discontinue all inducing sources like diuretics, laxatives,Acetate containing colloid sollution, exogenous alkali, combined antacid and cation exchange resin, sodium penicillins.