Menadione
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gloria Picoy [2]
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NOTE: Most over the counter (OTC) are not reviewed and approved by the FDA. However, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.
Overview
Menadione is a polycyclic aromatic ketone that is FDA approved for the treatment of joint pains, bruising, fatigue, abdominal discomfort, diarrhea, and hay fever.. Common adverse reactions include {{{adverseReactions}}}.
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
- For temporary relief of joint pains, bruising, fatigue, abdominal discomfort, diarrhea, and hay fever.
- Dosage: 1-10 drops under the tongue, 3 times a day
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Menadione in adult patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Menadione in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
Consult a physician for use in children under 12 years of age.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Menadione in pediatric patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Menadione in pediatric patients.
Contraindications
There is limited information regarding Menadione Contraindications in the drug label.
Warnings
- If pregnant or breast-feeding, ask a health care professional before use.
- Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
- Do not use if tamper evident seal is broken or missing. Store in a cool, dry place.
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Menadione Clinical Trials Experience in the drug label.
Postmarketing Experience
There is limited information regarding Menadione Postmarketing Experience in the drug label.
Drug Interactions
There is limited information regarding Menadione Drug Interactions in the drug label.
Use in Specific Populations
Pregnancy
Pregnancy Category (FDA):
There is no FDA guidance on usage of Menadione in women who are pregnant.
Pregnancy Category (AUS):
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Menadione in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Menadione during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Menadione in women who are nursing.
Pediatric Use
There is no FDA guidance on the use of Menadione in pediatric settings.
Geriatic Use
There is no FDA guidance on the use of Menadione in geriatric settings.
Gender
There is no FDA guidance on the use of Menadione with respect to specific gender populations.
Race
There is no FDA guidance on the use of Menadione with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Menadione in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Menadione in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Menadione in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Menadione in patients who are immunocompromised.
Administration and Monitoring
Administration
Oral
Monitoring
There is limited information regarding Menadione Monitoring in the drug label.
IV Compatibility
There is limited information regarding the compatibility of Menadione and IV administrations.
Overdosage
There is limited information regarding Menadione overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.
Pharmacology
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| C11H8O2 | |
| Molar mass | 172.18 g·mol−1 |
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| Template:Chembox header2 | Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
Mechanism of Action
There is limited information regarding Menadione Mechanism of Action in the drug label.
Structure
There is limited information regarding Menadione Structure in the drug label.
Pharmacodynamics
There is limited information regarding Menadione Pharmacodynamics in the drug label.
Pharmacokinetics
There is limited information regarding Menadione Pharmacokinetics in the drug label.
Nonclinical Toxicology
There is limited information regarding Menadione Nonclinical Toxicology in the drug label.
Clinical Studies
There is limited information regarding Menadione Clinical Studies in the drug label.
How Supplied
Menadione 1 FL OZ (30 ml)
Storage
There is limited information regarding Menadione Storage in the drug label.
Images
Drug Images
{{#ask: Page Name::Menadione |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}
Package and Label Display Panel
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Patient Counseling Information
There is limited information regarding Menadione Patient Counseling Information in the drug label.
Precautions with Alcohol
Alcohol-Menadione interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
Brand Names
- Menadione [2]
Look-Alike Drug Names
There is limited information regarding Menadione Look-Alike Drug Names in the drug label.
Drug Shortage Status
Price
References
The contents of this FDA label are provided by the National Library of Medicine.
- ↑ The Merck Index, 11th Edition, 5714
- ↑ "FDA LABEL: MENADIONE- menadione liquid".
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