Lysergic acid diethylamide pharmacokinetics and molecular data

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pharmacokinetics

Absorption

Antifungal/corticosteroids



Absorption

The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle, the integrity of the epidermal barrier and the use of occlusive dressings. Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin may increase percutaneous absorption of topical corticosteroids. Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids. Return to top

Antifungal/corticosteroids

Studies performed with LOTRISONE Cream and Lotion indicate that these topical combination antifungal/corticosteroids may have vasoconstrictor potencies in a range that is comparable to high potency topical corticosteroids. Therefore, use is not recommended in patients less than 17 years of age, in diaper dermatitis, and under occlusion. Return to top



Adapted from the FDA Package Insert.


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