Lysergic acid diethylamide pharmacokinetics and molecular data
The extent of percutaneous absorption of topical corticosteroids is determined by
many factors, including the vehicle, the integrity of the epidermal barrier and the
use of occlusive dressings. Topical
corticosteroids can be absorbed from normal intact skin. Inflammation and/or
other disease processes in the skin may increase percutaneous absorption of
topical corticosteroids. Occlusive dressings substantially increase the
percutaneous absorption of topical corticosteroids. Return to top
Studies performed with LOTRISONE Cream and Lotion indicate that these
topical combination antifungal/corticosteroids may have vasoconstrictor
potencies in a range that is comparable to high potency topical corticosteroids.
Therefore, use is not recommended in patients less than 17 years of age, in
diaper dermatitis, and under occlusion. Return to top
Adapted from the FDA Package Insert.