Lymphoplasmacytic lymphoma other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]

Overview

A PET scan can be helpful in spotting small collections of cancer cells, to detect whether an enlarged lymph node has lymphoma or not, to see the response of treatment, and to help decide whether an enlarged lymph node still contains lymphoma or is merely scar tissue after treatment.

Other Imaging Findings

PET-CT of the patient revealed FDG uptake at the second thoracic (Figure 3A, C) and fourth lumbar vertebrae. [https://openi.nlm.nih.gov/detailedresult.php?img=PMC3874980_TJH-30-409-g3&query=waldenstrom+macroglobulinaemia&it=xg&req=4&npos=45 Source: Lei Y. et al, Jilin University, Department of Hematology and Oncology, Changchun, China.
]
CT-PET axial segment showing high uptake in the paravertebral soft tissue regions at L4/L5.[https://openi.nlm.nih.gov/detailedresult.php?img=PMC4837273_CRIHEM2016-3931709.001&query=waldenstrom+macroglobulinaemia&it=xg&req=4&npos=68 Source: Halperin D. et al, Whipps Cross Hospital, London E11 1NR, UK.
]

References

  1. Valls L, Badve C, Avril S, Herrmann K, Faulhaber P, O'Donnell J; et al. (2016). "FDG-PET imaging in hematological malignancies". Blood Rev. 30 (4): 317–31. doi:10.1016/j.blre.2016.02.003. PMC 5298348. PMID 27090170.
  2. D'souza MM, Jaimini A, Bansal A, Tripathi M, Sharma R, Mondal A; et al. (2013). "FDG-PET/CT in lymphoma". Indian J Radiol Imaging. 23 (4): 354–65. doi:10.4103/0971-3026.125626. PMC 3932580. PMID 24604942.
  3. Friedberg, J. W. (2003). "PET Scans in the Staging of Lymphoma: Current Status". The Oncologist. 8 (5): 438–447. doi:10.1634/theoncologist.8-5-438. ISSN 1083-7159.
  4. Banwait, Ranjit; O'Regan, Kevin; Campigotto, Federico; Harris, Brianna; Yarar, Dilek; Bagshaw, Meghan; Leleu, Xavier; Leduc, Renee; Ramaiya, Nikhil; Weller, Edie; Ghobrial, Irene M. (2011). "The role of 18F-FDG PET/CT imaging in Waldenstrom macroglobulinemia". American Journal of Hematology. 86 (7): 567–572. doi:10.1002/ajh.22044. ISSN 0361-8609.
  5. Leleu, Xavier; Leduc, Renee; Rourke, Meghan; Harris, Brianna; Roccaro, Aldo M.; Yarar, Dilek; Farag, Jonathan; Ghobrial, Irene M. (2009). "PET/CT a New Marker of Response in Waldenstrom Macroglobulinemia (WM)". Blood. 114 (22): 1937–1937. doi:10.1182/blood.V114.22.1937.1937. ISSN 0006-4971.

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