Limbic encephalitis
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| Limbic encephalitis Classification and external resources | |
 | |
|---|---|
| The limbic system within the brain. | |
| ICD-10 | G13.1 |
| DiseasesDB | 30707 |
| MeSH | D020363 |
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Overview
Limbic encephalitis is a form of encephalitis.
In a small number of cases, the pathogens responsible for encephalitis attack primarily the limbic system (a collection of structures at the base of the brain responsible for basic autonomic functions), often causing memory deficits similar to those observed in Alzheimer's disease or Creutzfeldt-Jakob disease (although limbic encephalitis does not cause the same cognitive deficits as these diseases.[1] Unfortunately for 20% of people with the diagnosis of limbic encephalitis an MRI will not show any neurological abnormalities [2]
60% of the time, limbic encephalitis is paraneoplastic in origin. [3]
Paraneoplastic limbic encephalitis (PLE) is a particularly severe form of limbic encephalitis caused by neoplasms most commonly associated with small cell lung carcinoma. Whereas the majority of encephalitides are viral in nature, PLE is often associated with cancer. In fact, it is thought that up to 1 in 100 people with cancer have in fact got paraneoplastic limbic encephalitis which is commonly misdiagnosed as neurological diseases such as Alzheimer's.[4]
Diagnostic Findings
MRI
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References
- ↑ http://www.uiowa.edu/~c064s01/nr059.htm
- ↑ http://www.communityoncology.net/journal/articles/0408491.pdf
- ↑ http://www.communityoncology.net/journal/articles/0408491.pdf
- ↑ http://www.postgradmed.com/issues/2005/05_05/barrett_tab1.htm
External links
- vi_1/l/limbic_encephalitis article at GE's Medcyclopaedia
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
