Intussusception epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sargun Singh Walia M.B.B.S.[2]

Overview

Intussuception is a common pediatric emergency. The incidence of intussusception is estimated to be 2000 cases in children born in USA in the first year of life. The prevalence of intussusception does not vary with geographic and demographic distribution. Males are more commonly affected by intussusception than females. Male to female ratio is approximately 3:2. Intussusception most commonly affects children between the age of 6 months and 36 months. It can occur in adults but is mostly related to an underlying pathology (lead point).

Epidemiology and Demographics

Incidence

Case-fatality rate

  • A study was done in Spain, over a 12 year period. 94 cases were reviewed with incidence of intussusception, out of which majority were less than 1 year. Due to high rate of misdiagnosis and management, there was a high case fatality rate of 6400 per 100,000 cases.[2]

Age

The epidemiology of intussusception varies according to the age of the individual:[3]

  • 60% of children affected are younger than 1 year of age.[4]
  • 80 - 90% of children are less than 2 years old. [5]
  • 10% patients are over 5 years old.
  • 3-4% patients are over 10 years old.
  • 1% patients are younger than 3 months old.
  • Intussusception can occur in older patients as well. When it occurs in older patients it is usually due to a lead point.
  • Adults can also develop intussusception.
    • Child to adult ratio is believed to be more than 20:1.

Race

Gender

  • Males are more commonly affected by Intussusception than females. The male to female ratio is approximately 3:2 .[6]

References

  1. Fusco EE, Bhimji SS. PMID 28613732. Missing or empty |title= (help)
  2. Kuruvilla TT, Naraynsingh V, Raju GC, Manmohansingh LU (1988). "Intussusception in infancy and childhood". Trop Geogr Med. 40 (4): 342–6. PMID 3265814.
  3. Buettcher M, Baer G, Bonhoeffer J, Schaad UB, Heininger U (2007). "Three-year surveillance of intussusception in children in Switzerland". Pediatrics. 120 (3): 473–80. doi:10.1542/peds.2007-0035. PMID 17766518.
  4. Mandeville K, Chien M, Willyerd FA, Mandell G, Hostetler MA, Bulloch B (2012). "Intussusception: clinical presentations and imaging characteristics". Pediatr Emerg Care. 28 (9): 842–4. doi:10.1097/PEC.0b013e318267a75e. PMID 22929138.
  5. Mandeville K, Chien M, Willyerd FA, Mandell G, Hostetler MA, Bulloch B (2012). "Intussusception: clinical presentations and imaging characteristics". Pediatr Emerg Care. 28 (9): 842–4. doi:10.1097/PEC.0b013e318267a75e. PMID 22929138.
  6. Mandeville K, Chien M, Willyerd FA, Mandell G, Hostetler MA, Bulloch B (2012). "Intussusception: clinical presentations and imaging characteristics". Pediatr Emerg Care. 28 (9): 842–4. doi:10.1097/PEC.0b013e318267a75e. PMID 22929138.



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