Hyperandrogenism
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Many patients with hyperandrogenism have one of three syndromes:
- Polycystic Ovary Syndrome
- Congenital adrenal hyperplasia due to 21-hydroxylase deficiency
- Congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency
History and Symptoms
General appearance
- Muscular male body habitus (e.g. shoulder girdle)
- Android Obesity
Miscellaneous Changes
- Deepening of voice
- Clitorimegaly
- Increased Libido
Menstrual irregularity
Endocrine changes
- Hypertension
- Hyperlipidemia
- Glucose Intolerance
Skin changes
- Hirsutism involving face, chin, chest and perineum
- Alopecia
- Vertex or crown Hair Loss
- Bitemporal Hair Loss may also occur
- Acanthosis Nigricans (HAIR-AN Syndrome)
- Oily skin
- Acne Vulgaris
- Male sweat changes (malodorous perspiration)
Acknowledgements
The content on this page was first contributed by: C. Michael Gibson, M.S., M.D.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

