Hearing impairment medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Overview

Medical therapy includes removal of impacted cerumen via irrigation, manually, cerumenolytics, and under microscopy. Sudden onset SNHL can be treated with a single dose of steroids.

Medical Therapy[1]

Medical treatment includes the use of antivirals, steroids, and antibiotics. Antivirals have been used in cases caused by viral infection.

Virus Medical Therapy
Congenital CMV infection Ganciclovir (administered intravenously)
HSV-1 Acyclovir

antibiotics should be considered if symptoms of Otitis media in patients, do not improve in 3 days and/or they experience severe symptoms with high grade fever.

Cerumen impaction

Method 1. Cerumenolytics[2]

  • 3-5 drops of cerumenolytics are used 3 times/day to decrease impaction by lubrication and softening of earwax (oil-based) and/or fragmentation of skin cells within cerumen (water-based). It is a cheap and effective way to remove wax with minimal side effects.
  • Cerumenolytics must be cautiously used in patients with tympanic membrane perforation, rupture, or any active infections of the ear canal and eardrum.
Water-based cerumenolytics Oil-based cerumenolytics
Acetic acid,
Mineral oil
Hydrogen peroxide,
Debrox
Cerumenex
Murine

Method 2. Irrigation

  • Aural irrigation with water in patients is another effective method for wax removal. Irrigation with water is avoided in diabetic patients or use acidifying solutions after water irrigation.

Method 3. Manual extraction

  • An otolaryngologist manually extracts wax from the ear canal under otoscopic observation. A Stenosed ear canal due to a history of radiations to the head and neck or any trauma to the head can complicate the procedure.

Method 4. Vacuum extraction

Method 5. Extraction under binocular microscopy

Idiopathic sudden sensorineural hearing loss:[3][4]

  • Sudden hearing loss is a serious symptom that often requires an urgent visit to the hospital.
  • Firstly address distinguishing sensorineural hearing loss from conductive hearing loss at the time of presentation with hearing loss in a hospital setting. It can be done through weber and/or Rinne test or audiometry.
  • First-line treatment with oral steroids like Prednisone should be started within 14 days of symptoms onset.
  • Prednisone prescribed at 1 mg/kg of body weight per day at a maximum dose of 60 mg/d for 7–14 days, followed by tapering over a similar period. Prednisone has an anti-inflammatory effect and must be used cautiously in diabetic patients because of its effect on blood glucose. The time to treatment is definite and emphasized.
  • Another option for patients experiencing side effects with oral steroids is intratympanic steroids injections like dexamethasone but there's a risk for tympanic membrane perforation.
  • Hyperbaric oxygen therapy remains an option but only when combined with steroid therapy for oral or intratympanic initial treatment.
  • Antioxidants were removed from the list of treatments as they carry no clear-cut benefit.
  • Follow-up audiometry at end of treatment and also within 6 months posttreatment is added to reassess any residual or reoccurrence of hearing loss.

References

  1. Nieman CL, Oh ES (2020). "Hearing Loss". Ann Intern Med. 173 (11): ITC81–ITC96. doi:10.7326/AITC202012010. PMID 33253610 Check |pmid= value (help).
  2. Schwartz SR, Magit AE, Rosenfeld RM, Ballachanda BB, Hackell JM, Krouse HJ; et al. (2017). "Clinical Practice Guideline (Update): Earwax (Cerumen Impaction)". Otolaryngol Head Neck Surg. 156 (1_suppl): S1–S29. doi:10.1177/0194599816671491. PMID 28045591.
  3. Nieman CL, Oh ES (2020). "Hearing Loss". Ann Intern Med. 173 (11): ITC81–ITC96. doi:10.7326/AITC202012010. PMID 33253610 Check |pmid= value (help).
  4. Chandrasekhar SS, Tsai Do BS, Schwartz SR, Bontempo LJ, Faucett EA, Finestone SA; et al. (2019). "Clinical Practice Guideline: Sudden Hearing Loss (Update)". Otolaryngol Head Neck Surg. 161 (1_suppl): S1–S45. doi:10.1177/0194599819859885. PMID 31369359.