Halofantrine overdosage
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overdosage
In case of overdosage, vomiting should be induced, in conjunction with appropriate supportive measures, which should include ECG monitoring. The possibility of neurologic toxicity, especially decreased consciousness and seizures, should be evaluated. Dehydration secondary to gastrointestinal toxicity with diarrhea and vomiting may require treatment with intravenous fluid therapy.
Gastrointestinal distress with abdominal pain, vomiting, cramping, and diarrhea occurs at doses higher than the recommended therapeutic regimen. Palpitations have also been reported at these higher doses.[1]
References
- ↑ "http://www.accessdata.fda.gov/drugsatfda_docs/label/2002/20250s7s8lbl.pdf" (PDF). External link in
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Adapted from the FDA Package Insert.