Glycomics

Jump to: navigation, search

WikiDoc Resources for Glycomics

Articles

Most recent articles on Glycomics

Most cited articles on Glycomics

Review articles on Glycomics

Articles on Glycomics in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Glycomics

Images of Glycomics

Photos of Glycomics

Podcasts & MP3s on Glycomics

Videos on Glycomics

Evidence Based Medicine

Cochrane Collaboration on Glycomics

Bandolier on Glycomics

TRIP on Glycomics

Clinical Trials

Ongoing Trials on Glycomics at Clinical Trials.gov

Trial results on Glycomics

Clinical Trials on Glycomics at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Glycomics

NICE Guidance on Glycomics

NHS PRODIGY Guidance

FDA on Glycomics

CDC on Glycomics

Books

Books on Glycomics

News

Glycomics in the news

Be alerted to news on Glycomics

News trends on Glycomics

Commentary

Blogs on Glycomics

Definitions

Definitions of Glycomics

Patient Resources / Community

Patient resources on Glycomics

Discussion groups on Glycomics

Patient Handouts on Glycomics

Directions to Hospitals Treating Glycomics

Risk calculators and risk factors for Glycomics

Healthcare Provider Resources

Symptoms of Glycomics

Causes & Risk Factors for Glycomics

Diagnostic studies for Glycomics

Treatment of Glycomics

Continuing Medical Education (CME)

CME Programs on Glycomics

International

Glycomics en Espanol

Glycomics en Francais

Business

Glycomics in the Marketplace

Patents on Glycomics

Experimental / Informatics

List of terms related to Glycomics


Glycomics, an analogous term to genomics and proteomics, is the comprehensive study of glycomes (the entire complement of sugars, whether free or present in more complex molecules, of an organism), including genetic, physiologic, pathologic, and other aspects.[1][2] Glycomics "is the systematic study of all glycan structures of a given cell type or organism" and is a subset of glycobiology.[3] The term glycomics is derived from the chemical prefix for sweetness or a sugar, "glyco-", and was formed to follow the naming convention established by genomics (which deals with genes) and proteomics (which deals with proteins). The identity of the entirety of carbohydrates in an organism is thus collectively referred to as the glycome.

This area of research has to deal with an inherent level of complexity not seen in other areas of applied biology. 68 building blocks (molecules for DNA, RNA and proteins; categories for lipids; types of sugar linkages for saccharides) provide the structural basis for the molecular choreography that constitutes the entire life of a cell. DNA and RNA have four building blocks each (the nucleosides or nucleotides). Lipids are divided into eight categories based on ketoacyl and isoprene. Proteins have 20 (the amino acids). Saccharides have 32 types of sugar linkages.[4]. While these building blocks can be attached only linearly for proteins and genes, they can be arranged in a branched array for saccharides, further increasing the degree of compexity. Advances in glycomics are anticipated to be driven by improvements in molecular sequencing and bioinformatics, which is the computational organization and processing of sequence data.

See also

References

  1. Aoki-Kinoshita KF (2008). "An introduction to bioinformatics for glycomics research". PLoS Comput. Biol. 4 (5): e1000075. PMC 2398734Freely accessible. PMID 18516240. doi:10.1371/journal.pcbi.1000075.  Unknown parameter |month= ignored (help)
  2. Srivastava S (2008). "Move over proteomics, here comes glycomics". J. Proteome Res. 7 (5): 1799. PMID 18509903.  Unknown parameter |month= ignored (help)
  3. Cold Spring Harbor Laboratory Press Essentials of Glycobiology, Second Edition
  4. ucsd news article Do 68 Molecules Hold the Key to Understanding Disease? published September 3, 2008

Bibliography

  • C. Stan Tsai: Biomacromolecules. Wiley, Hoboken (New Jersey) 2007. ISBN 978-0-471-71397-5 Chapter 17, Pages 655-680

External links

Genomics topics
Genome project | Paleopolyploidy | Glycomics | Human Genome Project | Proteomics
Chemogenomics | Structural genomics | Pharmacogenetics | Pharmacogenomics | Toxicogenomics | Computational genomics
Bioinformatics | Cheminformatics | Systems biology
cs:Sacharomimetika

da:Glykobiologi de:Glykomikko:당쇄체학


Linked-in.jpg