Glycerol-1,2-cyclic-phosphate 2-phosphodiesterase

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In enzymology, a glycerol-1,2-cyclic-phosphate 2-phosphodiesterase (EC is an enzyme that catalyzes the chemical reaction

glycerol 1,2-cyclic phosphate + H2O glycerol 1-phosphate

Thus, the two substrates of this enzyme are glycerol 1,2-cyclic phosphate and H2O, whereas its product is glycerol 1-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is rac-glycerol-1,2-cyclic-phosphate 2-glycerophosphohydrolase. This enzyme is also called rac-glycerol 1:2-cyclic phosphate 2-phosphodiesterase.


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  • Clarke N, Dawson RM (1978). "rac-Glycerol 1:2-cyclic phosphate 2-phosphodiesterase, a new soluble phosphodiesterase of mammalian tissues". Biochem. J. 173: 579&ndash, 89. PMID 212014.

External links

The CAS registry number for this enzyme class is 69458-89-5.

Gene Ontology (GO) codes