Ganglioglioma differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Ganglioglioma must be differentiated from dysembryoplastic neuroepithelial tumors, pleomorphic xanthoastrocytoma, oligodendroglioma, desmoplastic infantile ganglioglioma, astrocytoma, ependymoma, and transverse myelitis.

Ganglioglioma must be differentiated from:^[1]


Differential Diagnosis	Differentiating Features

Dysembryoplastic neuroepithelial tumors (DNET)	Contrast enhancement uncommon "Bubbly appearance" common
Pleomorphic xanthoastrocytoma (PXA)	Contrast enhancement prominent Dural tail sign present
Oligodendroglioma	Calcification common
Desmoplastic infantile ganglioglioma	Young children Dural involvement prominent Large, often multiple lesions
Astrocytoma Ependymoma Transverse myelitis	Often a differential diagnosis of ganglioglioma when ganglioglioma is located in the spinal cord

↑ DDx of ganglioglioma. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/ganglioglioma