Formylaspartate deformylase

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In enzymology, a formylaspartate deformylase (EC 3.5.1.8) is an enzyme that catalyzes the chemical reaction

N-formyl-L-aspartate + H2O formate + L-aspartate

Thus, the two substrates of this enzyme are N-formyl-L-aspartate and H2O, whereas its two products are formate and L-aspartate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-formyl-L-aspartate amidohydrolase. This enzyme is also called formylaspartic formylase (formylase I, formylase II). This enzyme participates in histidine metabolism and glyoxylate and dicarboxylate metabolism.

References

  • IUBMB entry for 3.5.1.8
  • BRENDA references for 3.5.1.8 (Recommended.)
  • PubMed references for 3.5.1.8
  • PubMed Central references for 3.5.1.8
  • Google Scholar references for 3.5.1.8
  • Ohmura E and Hayaishi O (1957). "Enzymatic conversion of formylaspartic acid to aspartic acid". J. Biol. Chem. 227: 181&ndash, 190.

External links

The CAS registry number for this enzyme class is 9025-09-6.

Gene Ontology (GO) codes


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