Epithelioid cell
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Epithelioid histiocytes (Epithelioid cells) are activated macrophages resembling epithelial cells:[1] elongated, with finely granular, pale eosinophilic (pink) cytoplasm and central, ovoid nucleus(oval or elongate), which is less dense than that of a lymphocyte. They have indistinct shape contour, often appear to merge into one another and form aggregates.
Clinical significance
The presence of epithelioid histiocytes may characterise some pathologic conditions, mainly granulomatous inflammation, including Orofacial granulomatosis[2]. The excessive proliferation of them on skin causes reticulohistiocytoma and somewhat it is associated with arthritis.
See also
References
- ↑ Dorlands Medical Dictionary:epithelioid cell.
- ↑ Bogenrieder T, Rogler G, Vogt T, Landthaler M, Stolz W (2003). "Orofacial granulomatosis as the initial presentation of Crohn's disease in an adolescent". Dermatology (Basel) 206 (3): 273–8. doi:10.1159/000068900. PMID 12673090.
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
