Ebsteins anomaly of the tricuspid valve risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Claudia P. Hochberg, M.D.
Overview
The development of Ebstein's anomaly is associated with the administration of Lithium Carbonate during the first trimester or benzodiazepines during pregnancy. Maternal exposure to varnishing substances is also a risk factor as is a previous history of fetal loss in the mother.
Risk factors
- Lithium exposure during pregnancy.[1][2][3]
- Benzodiazepine use.
- Second-hand cigarette smoke exposure at home.
- Family history of congenital heart defect(CHD).
References
- ↑ Downing KF, Riehle-Colarusso T, Gilboa SM, Lin AE, Oster ME, Tinker SC, Farr SL (June 2019). "Potential risk factors for Ebstein anomaly, National Birth Defects Prevention Study, 1997-2011". Cardiol Young. 29 (6): 819–827. doi:10.1017/S1047951119000970. PMID 31159903.
- ↑ Hoyt AT, Canfield MA, Romitti PA, Botto LD, Anderka MT, Krikov SV, Tarpey MK, Feldkamp ML (November 2016). "Associations between maternal periconceptional exposure to secondhand tobacco smoke and major birth defects". Am. J. Obstet. Gynecol. 215 (5): 613.e1–613.e11. doi:10.1016/j.ajog.2016.07.022. PMID 27443814.
- ↑ Chung KC, Kowalski CP, Kim HM, Buchman SR (February 2000). "Maternal cigarette smoking during pregnancy and the risk of having a child with cleft lip/palate". Plast. Reconstr. Surg. 105 (2): 485–91. doi:10.1097/00006534-200002000-00001. PMID 10697150.