Dolichylphosphate-mannose phosphodiesterase

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In enzymology, a dolichylphosphate-mannose phosphodiesterase (EC is an enzyme that catalyzes the chemical reaction

dolichyl beta-D-mannosyl phosphate + H2O dolichyl phosphate + D-mannose

Thus, the two substrates of this enzyme are dolichyl beta-D-mannosyl phosphate and H2O, whereas its two products are dolichyl phosphate and D-mannose.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase. This enzyme is also called mannosylphosphodolichol phosphodiesterase.


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  • Tomita Y, Motokawa Y (1987). "Characterization and partial purification of a novel mannosylphosphodolichol phosphodiesterase from chicken liver microsomes". Eur. J. Biochem. 170: 363&ndash, 8. PMID 2826159.

External links

The CAS registry number for this enzyme class is 111839-07-7.

Gene Ontology (GO) codes