Disseminated intravascular coagulation epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2]
Overview
The incidence of DIC is different in different diseases as it is almost always related to a life threatening condition. It depends on the cause of DIC such as cancer, infection, trauma and Obstetrical complications. The incidence of DIC is different in different diseases as it is almost always related to a life threatening condition. It depends on the cause of DIC such as cancer, infection, trauma and obstetrical complications. The prevalence of DIC depends on the clinical settings, higher versus low acquity settings. The data sometimes may underestimate the incidence of trasient or mild cases of DIC.
Epidemiology and Demographics
Incidence
- The incidence of DIC is different in different diseases as it is almost always related to a life threatening condition. It depends on the cause of DIC such as cancer, infection, trauma and Obstetrical complications[1][2]
- In 2010, the incidence of DIC was estimated to be 26.2 cases per 100,000 individuals worldwide.[3][4][5]
Prevalence
- The prevalence of DIC depends on the clinical settings, higher versus low acquity settings.
- In 2013, the prevalence of DIC was estimated to be 46.8% (292/624) [6][7][8][9]
Age
- Patients of all age groups may develop DIC.
Race
- There is no racial predilection to DIC
Gender
- DIC affects men and women equally
Developing Countries
- The prevalence of DIC depends on the clinical settings, higher versus low acquity settings.
References
- ↑ Levi M, Ten Cate H (August 1999). "Disseminated intravascular coagulation". N. Engl. J. Med. 341 (8): 586–92. doi:10.1056/NEJM199908193410807. PMID 10451465.
- ↑ Sallah S, Wan JY, Nguyen NP, Hanrahan LR, Sigounas G (September 2001). "Disseminated intravascular coagulation in solid tumors: clinical and pathologic study". Thromb. Haemost. 86 (3): 828–33. PMID 11583315.
- ↑ Singh B, Hanson AC, Alhurani R, Wang S, Herasevich V, Cartin-Ceba R, Kor DJ, Gangat N, Li G (May 2013). "Trends in the incidence and outcomes of disseminated intravascular coagulation in critically ill patients (2004-2010): a population-based study". Chest. 143 (5): 1235–1242. doi:10.1378/chest.12-2112. PMID 23139140.
- ↑ Smith OP, White B, Vaughan D, Rafferty M, Claffey L, Lyons B, Casey W (November 1997). "Use of protein-C concentrate, heparin, and haemodiafiltration in meningococcus-induced purpura fulminans". Lancet. 350 (9091): 1590–3. PMID 9393338.
- ↑ Gando S, Nanzaki S, Kemmotsu O (January 1999). "Disseminated intravascular coagulation and sustained systemic inflammatory response syndrome predict organ dysfunctions after trauma: application of clinical decision analysis". Ann. Surg. 229 (1): 121–7. PMC 1191617. PMID 9923809.
- ↑ Gando S, Saitoh D, Ogura H, Fujishima S, Mayumi T, Araki T, Ikeda H, Kotani J, Kushimoto S, Miki Y, Shiraishi S, Suzuki K, Suzuki Y, Takeyama N, Takuma K, Tsuruta R, Yamaguchi Y, Yamashita N, Aikawa N (June 2013). "A multicenter, prospective validation study of the Japanese Association for Acute Medicine disseminated intravascular coagulation scoring system in patients with severe sepsis". Crit Care. 17 (3): R111. doi:10.1186/cc12783. PMC 4056654. PMID 23787004.
- ↑ Hulka F, Mullins RJ, Frank EH (September 1996). "Blunt brain injury activates the coagulation process". Arch Surg. 131 (9): 923–7, discussion 927–8. PMID 8790176.
- ↑ Gilbert WM, Danielsen B (June 1999). "Amniotic fluid embolism: decreased mortality in a population-based study". Obstet Gynecol. 93 (6): 973–7. PMID 10362165.
- ↑ Sibai BM, Ramadan MK, Usta I, Salama M, Mercer BM, Friedman SA (October 1993). "Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome)". Am. J. Obstet. Gynecol. 169 (4): 1000–6. PMID 8238109.