Diphosphate-purine nucleoside kinase

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In enzymology, a diphosphate-purine nucleoside kinase (EC 2.7.1.143) is an enzyme that catalyzes the chemical reaction

diphosphate + a purine nucleoside phosphate + a purine mononucleotide

Thus, the two substrates of this enzyme are diphosphate and purine nucleoside, whereas its two products are phosphate and purine mononucleotide.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is diphosphate:purine nucleoside phosphotransferase. This enzyme is also called pyrophosphate-purine nucleoside kinase.

References

  • IUBMB entry for 2.7.1.143
  • BRENDA references for 2.7.1.143 (Recommended.)
  • PubMed references for 2.7.1.143
  • PubMed Central references for 2.7.1.143
  • Google Scholar references for 2.7.1.143
  • Tryon VV, Pollack D (1984). "Purine metabolism in Acholeplasma laidlawii B: novel PPi-dependent nucleoside kinase activity". J. Bacteriol. 159: 265&ndash, 70. PMID 6330034.
  • Tryon VV, Pollack JD (1985). "Distinctions in Mollicutes purine metabolism: pyrophosphate-dependent nucleoside kinase and dependence on guanylate salvage". Int. J. Systematic Bacteriol. 35: 497&ndash, 501.

External links

The CAS registry number for this enzyme class is 70356-41-1.

Gene Ontology (GO) codes


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