Diffuse panbronchiolitis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Overview

History

Symptoms

DPB can be characterized by a number of symptoms and histological features (those detected by analysis of tissues).

If left untreated, as DPB progresses, signs of bronchiectasis begin to present themselves. These symptoms include chronic shortness of breath, severe cough, pooling of sputum, thickening of bronchiolar walls, hypoxemia, and dilation (enlargement) of the bronchiolar passages.[1][2] This eventually becomes life-threatening, leading to respiratory failure.[1]

References

  1. 1.0 1.1 Homma H, Yamanaka A, Tanimoto S, Tamura M, Chijimatsu Y, Kira S, Izumi T (1983). "Diffuse panbronchiolitis. A disease of the transitional zone of the lung". Chest. 83 (1): 63–69. PMID 6848335.
  2. Fitzgerald JE, King TE Jr., Lynch DA, Tuder RM, Schwarz MI (1996). "Diffuse panbronchiolitis in the United States". Am J Respir Crit Care Med. 154 (2 pt. 1): 497–503. PMID 8756828.