D-glutamate(D-aspartate) oxidase

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In enzymology, a D-glutamate(D-aspartate) oxidase (EC 1.4.3.15) is an enzyme that catalyzes the chemical reaction

D-glutamate + H2O + O2 2-oxoglutarate + NH3 + H2O2

The 3 substrates of this enzyme are D-glutamate, H2O, and O2, whereas its 3 products are 2-oxoglutarate, NH3, and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with oxygen as acceptor. The systematic name of this enzyme class is D-glutamate(D-aspartate):oxygen oxidoreductase (deaminating). Other names in common use include D-glutamic-aspartic oxidase, and D-monoaminodicarboxylic acid oxidase. This enzyme participates in alanine and aspartate metabolism. It employs one cofactor, FAD.

References

  • IUBMB entry for 1.4.3.15
  • BRENDA references for 1.4.3.15 (Recommended.)
  • PubMed references for 1.4.3.15
  • PubMed Central references for 1.4.3.15
  • Google Scholar references for 1.4.3.15
  • Mizushima S (1957). "Purified D-glutamic-aspartic oxidase of Aspergillus ustus". J. Gen. Appl. Microbiol. 3: 233&ndash, 239.

External links

Gene Ontology (GO) codes



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