Cytokinin dehydrogenase

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In enzymology, a cytokinin dehydrogenase (EC is an enzyme that catalyzes the chemical reaction

N6-dimethylallyladenine + acceptor + H2O adenine + 3-methylbut-2-enal + reduced acceptor

The 3 substrates of this enzyme are N6-dimethylallyladenine, acceptor, and H2O, whereas its 3 products are adenine, 3-methylbut-2-enal, and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with other acceptors. The systematic name of this enzyme class is N6-dimethylallyladenine:acceptor oxidoreductase. Other names in common use include N6-dimethylallyladenine:(acceptor) oxidoreductase, 6-N-dimethylallyladenine:acceptor oxidoreductase, OsCKX2, CKX, and cytokinin oxidase/dehydrogenase.

Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1W1O, 1W1Q, 1W1R, 1W1S, 2EXR, and 2Q4W.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Galuszka P, Frebort I, Sebela M, Sauer P, Jacobsen S, Pec P (2001). "Cytokinin oxidase or dehydrogenase? Mechanism of cytokinin degradation in cereals". Eur. J. Biochem. 268: 450&ndash, 61. PMID 11168382.

External links

Gene Ontology (GO) codes