Corticosterone

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Corticosterone
File:Corticosterone.svg
200px
Identifiers
CAS number 50-22-6
PubChem 5753
MeSH Corticosterone
Properties
Molecular formula C21H30O4
Molar mass 346.461
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Corticosterone is a 21 carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.

Functions

In many species, including rodents, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.

However, in humans, corticosterone is produced primarily in the zona glomerulosa of the adrenal cortex. It has only weak glucocorticoid and mineralocorticoid potencies in humans and is important mainly as an intermediate in the steroidogenic pathway from pregnenolone to aldosterone.

Additional images


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