Coagulopathy

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Coagulopathy Classification and external resources
ICD-10	D65.-D68.
ICD-9	286
DiseasesDB	29158
MeSH	D001778

WikiDoc Resources for Coagulopathy
Articles
Most recent articles on Coagulopathy Most cited articles on Coagulopathy Review articles on Coagulopathy Articles on Coagulopathy in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Coagulopathy Images of Coagulopathy Photos of Coagulopathy Podcasts & MP3s on Coagulopathy Videos on Coagulopathy
Evidence Based Medicine
Cochrane Collaboration on Coagulopathy Bandolier on Coagulopathy TRIP on Coagulopathy
Clinical Trials
Ongoing Trials on Coagulopathy at Clinical Trials.gov Trial results on Coagulopathy Clinical Trials on Coagulopathy at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Coagulopathy NICE Guidance on Coagulopathy NHS PRODIGY Guidance FDA on Coagulopathy CDC on Coagulopathy
Books
Books on Coagulopathy
News
Coagulopathy in the news Be alerted to news on Coagulopathy News trends on Coagulopathy
Commentary
Blogs on Coagulopathy
Definitions
Definitions of Coagulopathy
Patient Resources / Community
Patient resources on Coagulopathy Discussion groups on Coagulopathy Patient Handouts on Coagulopathy Directions to Hospitals Treating Coagulopathy Risk calculators and risk factors for Coagulopathy
Healthcare Provider Resources
Symptoms of Coagulopathy Causes & Risk Factors for Coagulopathy Diagnostic studies for Coagulopathy Treatment of Coagulopathy
Continuing Medical Education (CME)
CME Programs on Coagulopathy
International
Coagulopathy en Espanol Coagulopathy en Francais
Business
Coagulopathy in the Marketplace Patents on Coagulopathy
Experimental / Informatics
List of terms related to Coagulopathy

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Overview

Coagulopathy is a medical term for a defect in the body's mechanism for blood clotting. While there are several possible causes they generally result in excessive bleeding and a lack of clotting.

Hemophilia is one type of congenital disease characterized by coagulopathy; these are examples of severe lack of blood clotting.

Acquired causes of coagulopathy include anticoagulation with warfarin, liver failure, and disseminated intravascular coagulation. Additionally, the haemotoxic venom from certain species of snakes can cause this condition e.g. Bothrops, rattlesnakes and other species of viper.

Differential Diagnosis of Bleeding Diatheses:

• Haemophilia
• von Willebrand Disease
• Glanzmann thrombasthenia
• Bernard-Soulier syndrome
• Scurvy
• Leukemia ^{[1] [2]}

References

1. ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
2. ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X

See also

• Coagulation

v • d • e Pathology: hematology, myeloid hematologic disease (primarily D50-D77, 280-289)
RBCs/ hemoglobinopathy	+ Polycythemia - Macrocytosis - Anemia Nutritional Iron deficiency anemia (Plummer-Vinson syndrome), Megaloblastic anemia (Pernicious anemia) Hemolytic Hereditary enzyme: G6PD Deficiency - Pyruvate kinase deficiency - Triosephosphate isomerase deficiency hemoglobin: Thalassemia - Sickle-cell disease/trait membrane: Hereditary spherocytosis - Hereditary elliptocytosis - Hereditary stomatocytosis Acquired Autoimmune (Warm, Cold), HUS, MAHA, PNH, PCH, Myelophthisic Aplastic Acquired PRCA, Diamond-Blackfan anemia, Fanconi anemia, Sideroblastic anemia Blood tests Normocytic - Microcytic - Macrocytic - Normochromic - Hypochromic Other Methemoglobinemia
Coagulation/platelets/ coagulopathy/ bleeding diathesis	+ Hypercoagulability primary: Antithrombin III deficiency - Protein C deficiency/Activated protein C resistance/Protein S deficiency/Factor V Leiden - Hyperprothrombinemia acquired: DIC (Congenital afibrinogenemia, Purpura fulminans) - autoimmune (Antiphospholipid) Other Essential thrombocytosis - clotting factor: Hemophilia (A/VIII, B/IX, C/XI) • Von Willebrand disease • Hypoprothrombinemia/II - XIII platelet function: Bernard-Soulier syndrome - Glanzmann's thrombasthenia - Gray platelet syndrome - May Hegglin anomaly - Pelger-Huet anomaly Purpura: Henoch-Schönlein, ITP (Evans syndrome), TTP Thrombocytopenia (Heparin-induced thrombocytopenia)
Monocytes/ macrophages	+ Histiocytosis WHO-I (Langerhans cell histiocytosis) WHO-II/non-Langerhans-cell (Juvenile xanthogranuloma, Hemophagocytic lymphohistiocytosis) WHO-III/malignant (Acute monocytic leukemia, Malignant histiocytosis, Erdheim-Chester disease) Other Chronic granulomatous disease -cytosis: Monocytosis - -penia: Monocytopenia
Granulocytes	+ -cytosis: granulocytosis (Neutrophilia, Eosinophilia, Basophilia) - -penia: Granulocytopenia/agranulocytosis (Neutropenia/Kostmann syndrome, Eosinopenia, Basopenia)
See also hematological malignancy and immune disorders

v • d • e WikiDoc Research Resources for Coagulopathy
Articles on Coagulopathy	Most recent articles on Coagulopathy • Most cited articles on Coagulopathy • Review articles on Coagulopathy • Articles on Coagulopathy in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Coagulopathy	Powerpoint slides on Coagulopathy • Images of Coagulopathy • Photos of Coagulopathy • Podcasts & MP3s on Coagulopathy • Videos on Coagulopathy
Evidence Based Medicine Regarding Coagulopathy	Cochrane Collaboration on Coagulopathy • Bandolier on Coagulopathy • TRIP on Coagulopathy
Cost Effectiveness of Coagulopathy	Cost Effectiveness of Coagulopathy
Clinical Trials Involving Coagulopathy	Ongoing Trials on Coagulopathy at Clinical Trials.gov • Trial results on Coagulopathy • Clinical Trials on Coagulopathy at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Coagulopathy	US National Guidelines Clearinghouse on Coagulopathy • NICE Guidance on Coagulopathy • NHS PRODIGY Guidance • FDA on Coagulopathy • CDC on Coagulopathy
Textbook Information on Coagulopathy	Books and Textbook Information on Coagulopathy
Pharmacology Resources on Coagulopathy	Dosing of Coagulopathy • Drug interactions with Coagulopathy • Side effects of Coagulopathy • Allergic reactions to Coagulopathy • Overdose information on Coagulopathy • Carcinogenicity information on Coagulopathy • Coagulopathy in pregnancy • Pharmacokinetics of Coagulopathy •
Genetics, Pharmacogenomics, and Proteinomics of Coagulopathy	Genetics of Coagulopathy • Pharmacogenomics of Coagulopathy • Proteomics of Coagulopathy
Newstories on Coagulopathy	Coagulopathy in the news • Be alerted to news on Coagulopathy • News trends on Coagulopathy
Commentary on Coagulopathy	Blogs on Coagulopathy
Patient Resources on Coagulopathy	Patient resources on Coagulopathy • Discussion groups on Coagulopathy • Patient Handouts on Coagulopathy • Directions to Hospitals Treating Coagulopathy • Risk calculators and risk factors for Coagulopathy
Healthcare Provider Resources on Coagulopathy	Symptoms of Coagulopathy • Causes & Risk Factors for Coagulopathy • Diagnostic studies for Coagulopathy • Treatment of Coagulopathy
Continuing Medical Education (CME) Programs on Coagulopathy	CME Programs on Coagulopathy
International Resources on Coagulopathy	Coagulopathy en Espanol • Coagulopathy en Francais
Business Resources on Coagulopathy	Coagulopathy in the Marketplace • Patents on Coagulopathy
Informatics Resources on Coagulopathy	List of terms related to Coagulopathy