Choroid plexus

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Brain: Choroid plexus
Gray708.svg
Scheme of roof of fourth ventricle. The arrow is in the foramen of Magendie.
1: inferior medullary velum
2: Choroid plexus
3: Cerebellomedullary cistern of subarachnoid cavity
4: Central canal
5: Corpora quadrigemina
6: Cerebral peduncle
7: Superior medullary velum
8: Ependymal lining of ventricle
9: Pontine cistern of subarachnoid cavity
Gray723.png
Coronal section of lateral and third ventricles.
Latin plexus choroideus
Gray's subject #187 798
NeuroNames ancil-456
MeSH Choroid+Plexus

The choroid plexus is the area on the ventricles of the brain where cerebrospinal fluid (CSF) is produced by modified ependymal cells.

Choroid plexus is present in all components of the ventricular system except for the cerebral aqueduct and the occipital and frontal horns of the lateral ventricles.

It is found in the superior part of the inferior horn of the lateral ventricles. It follows up along this boundary, continuous with the inferior of the body of the lateral ventricles. It passes into the interventricular foramen, and is present at the top of the third ventricle.

There is also choroid plexus on the fourth ventricle, on the section closest to the bottom half of the cerebellum.

Structure of the choroid plexus

The choroid plexus consists of many capillaries, separated from the subarachnoid space by pia mater and choroid ependymal cells. Liquid filters through these cells from blood to become cerebrospinal fluid. There is also much active transport of substances into, and out of, the CSF as it is made.

Pathology

During embryological development, some fetuses may form choroid plexus cysts. These fluid-filled cysts are likely harmless, however if found during an ultrasound, they may be an indicator of chromosomal abnormalities in the fetus, especially trisomy 21 (Down's syndrome), and further testing may be indicated.

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