Chorioamnionitis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Adnan Ezici, M.D[2]

Overview

The prevalence of chorioamnionitis was estimated to be approximately 4,000 cases per 100,000 individuals worldwide. Chorioamnionitis more commonly affects individuals < 18 years of age. Gestational age is also a strong predictor of chorioamnionitis with increased prevalence in people who delivered between 21 and 24 weeks of gestation. Male infants are more commonly affected than females. Chorioamnionitis usually affects individuals of Hispanics and Asian/Pacific Islanders.

Epidemiology and Demographics

Prevelance

  • Worldwide, the prevalence of chorioamnionitis is approximately 4,000 per 100,000 persons.[1]
    • In developed countries, the prevalence of chorioamnionitis is 970 per 100,000 persons.[2]

Age

  • Chorioamnionitis is more commonly seen in patients < 18 years of age.[2]

Gestational Age

  • The prevalence of chorioamnionitis decreases with gestational age until 37-40 weeks of gestation, then slightly increases again.
    • Chorioamnionitis most commonly affects patients who delivered between 21 and 24 weeks of gestation.
      • It is worth mentioning that the frequency of chorioamnionitis is approximately 94% in this group. [3]

Gender

  • Male infants are more commonly affected with chorioamnionitis than female infants.[2]

Race

  • Chorioamnionitis usually affects individuals of non-White races. White individuals are less likely to develop chorioamnionitis.[2]
    • Chorioamnionitis is more prevalent in Hispanics and Asian/Pacific Islanders.
    • Although individuals of the Black race usually less affected than Hispanics and Asian/Pacific Islanders, the prevalence of chorioamnionitis is higher in individuals of the black race than whites.

References

  1. Fowler JR, Simon LV. PMID 30335284. Missing or empty |title= (help)
  2. 2.0 2.1 2.2 2.3 Malloy MH (August 2014). "Chorioamnionitis: epidemiology of newborn management and outcome United States 2008". J Perinatol. 34 (8): 611–5. doi:10.1038/jp.2014.81. PMID 24786381.
  3. Kim CJ, Romero R, Chaemsaithong P, Chaiyasit N, Yoon BH, Kim YM (October 2015). "Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance". Am J Obstet Gynecol. 213 (4 Suppl): S29–52. doi:10.1016/j.ajog.2015.08.040. PMC 4774647. PMID 26428501.

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