Central cord syndrome

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Central Cord Syndrome
Classification and external resources
Central cord syndrome is top diagram
ICD-9 952.18
DiseasesDB 33409
eMedicine pmr/22 
MeSH D020210

Central cord syndrome (CCS) is an acute cervical spinal cord injury (SCI), characterized by disproportionately greater motor impairment in upper compared to lower extremities, bladder dysfunction, and variable degree of sensory loss below the level of injury. This syndrome is unlike a complete lesion, that causes loss of all sensation and movement below the level of the injury. First described by Schneider in 1954,[1] CCS has been reported to occur more frequently among older persons with cervical spondylosis who sustain hyperextension injury. Though it also may occur in persons of any age. CCS is the most common incomplete SCI syndrome.

CCS most often occurs after hyperextension injury in an individual with long-standing cervical spondylosis. Historically, spinal cord damage was believed to originate from concussion or contusion of the cord with stasis of axoplasmic flow, causing edematous injury rather than destructive hematomyelia. More recently, autopsy studies have demonstrated that CCS may be caused by bleeding into the central part of the cord, portending less favorable prognosis. Studies also have shown that CCS probably is associated with axonal disruption in the lateral columns at the level of the injury to the spinal cord with relative preservation of the grey matter.

In the US the prevalence rate is 15.7-25% however this syndrome is generally associated with favorable prognosis for some degree of neurologic and functional recovery. CCS predominantly affects men more than women, similar to all other SCI.

See also

Spinal cord injury

References

  1. Schneider RC, Cherry G, Pantek H (1954). "The syndrome of acute central cervical spinal cord injury; with special reference to the mechanisms involved in hyperextension injuries of cervical spine". J. Neurosurg. 11 (6): 546-77. PMID 13222164.

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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