Carbohydrate (chondroitin 4) sulfotransferase 13

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VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Carbohydrate (chondroitin 4) sulfotransferase 13 is a protein that is encoded in humans by the CHST13 gene.[1]

Function

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices.

References

  1. "Entrez Gene: Carbohydrate (chondroitin 4) sulfotransferase 13".

Further reading

  • Kang HG, Evers MR, Xia G, Baenziger JU, Schachner M (September 2002). "Molecular cloning and characterization of chondroitin-4-O-sulfotransferase-3. A novel member of the HNK-1 family of sulfotransferases". The Journal of Biological Chemistry. 277 (38): 34766–72. doi:10.1074/jbc.M204907200. PMID 12080076.
  • Valente B, Campos PA, do Rosário VE, Silveira H (October 2010). "Natural frequency of polymorphisms linked to the chondroitin 4-sulfotransferase genes and its association with placental malaria". Transactions of the Royal Society of Tropical Medicine and Hygiene. 104 (10): 687–9. doi:10.1016/j.trstmh.2010.05.005. PMID 20580388.
  • Hiraoka N, Nakagawa H, Ong E, Akama TO, Fukuda MN, Fukuda M (June 2000). "Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family". The Journal of Biological Chemistry. 275 (26): 20188–96. doi:10.1074/jbc.M002443200. PMID 10781601.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.