CBV regimen

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords: BCNU/CTX/VP-16; Carmustine/Cyclophosphamide/Etoposide; CBV

Overview

CBV regimen refers to cyclophosphamide (Cytoxan), carmustine (BCNU), and etoposide (VP-16), three drugs in a chemotherapy regimen commonly given to lymphoma patients in conjunction with stem cell therapy.[1]

Regimen

CCyclophosphamide

BCarmustine (BCNU)

VEtoposide (VP-160)

Indications

References

  1. Skeel, Roland T. Handbook of Cancer Chemotherapy, 6th Edition. Philadelphia: Lipincott, Williams, & Wilkins, 2003. Page 172-3, Table 5.4: "Common preparative regimens for high-dose therapy without total-body irradiation."
  2. Zander AR, Culbert S, Jagannath S, Spitzer G, Keating M, Larry N; et al. (1987). "High dose cyclophosphamide, BCNU, and VP-16 (CBV) as a conditioning regimen for allogeneic bone marrow transplantation for patients with acute leukemia". Cancer. 59 (6): 1083–6. PMID 3545428.