Benserazide
Jump to navigation
Jump to search
File:Benserazide.svg | |
Clinical data | |
---|---|
Pregnancy category |
|
Legal status | |
Legal status | |
Pharmacokinetic data | |
Excretion | Renal and fecal |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
Chemical and physical data | |
Formula | C10H15N3O5 |
Molar mass | 293.71 g/mol |
Benserazide is an inhibitor of DOPA decarboxylase that does not enter the central nervous system. It is often given in combination with L-DOPA (levodopa) as Co-Beneldopa (BAN) (e.g. Madopar® by Roche in UK) in the treatment of Parkinson's disease to prevent the conversion of L-DOPA to dopamine in the periphery (due to its molecular size it can not penetrate the blood brain barrier) the amount that reaches the central nervous system and reducing the required dose, and also decreasing side effects due to the presence of dopamine in the system (outside of the central nervous system). It has no antiparkinson actions when given alone.
Categories:
- Pages with script errors
- Pages with broken file links
- Drugs with non-standard legal status
- E number from Wikidata
- ECHA InfoCard ID from Wikidata
- Chemical articles with unknown parameter in Infobox drug
- Articles without EBI source
- Chemical pages without ChemSpiderID
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
- Articles without UNII source
- Drugs missing an ATC code
- Articles containing unverified chemical infoboxes
- Antiparkinsonian agents