Baeyer-Drewson indigo synthesis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


The Baeyer-Drewsen indigo synthesis (1882) is an organic reaction in which indigo is prepared from o-nitrobenzaldehyde and acetone [1] [2]

Baeyer-Drewson indigo synthesis

The reaction is classified as a Aldol condensation.


  1. Adolf Baeyer, Viggo Drewsen (1882). "Darstellung von Indigblau aus Orthonitrobenzaldehyd". Berichte der deutschen chemischen Gesellschaft 15 (2): 2856–2864. doi:10.1002/cber.188201502274.
  2. Helmut Schmidt (1997). "Indigo - 100 Jahre industrielle Synthese". Chemie in unserer Zeit 31 (3): 121–128. doi:10.1002/ciuz.19970310304.

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