Aortic dissection treatment

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Aortic dissection Microchapters

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Differentiating Aortic dissection from other Diseases

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Management during Pregnancy

Case Studies

Case #1


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Treatment

The risk of death due to aortic dissection is highest in the first few hours after the dissection begins, and decreases afterwards. Because of this, the therapeutic strategies differ for treatment of an acute dissection compared to a chronic dissection. An acute dissection is one in which the individual presents within the first two weeks. If the individual has managed to survive this window period, his prognosis is improved. About 66% of all dissections present in the acute phase.

In all individuals with aortic dissections, medication should be used to control high blood pressure, if present.

In the case of an acute dissection, once diagnosis has been confirmed, the choice of treatment depends on the location of the dissection. For ascending aortic dissection, surgical management is superior to medical management. On the other hand, in the case of an uncomplicated distal aortic dissections (including abdominal aortic dissections), medical management is preferred over surgical treatment [1]

Individuals who present two weeks after the onset of the dissection are said to have chronic aortic dissections. These individuals have been self-selected as survivors of the acute episode, and can be treated with medical therapy as long as they are stable.

Medical management is appropriate in individuals with an uncomplicated distal dissection, a stable dissection isolated to the aortic arch, and stable chronic dissections. Patient selection for medical management is very important. Stable individuals who present with an acute distal dissection (typically treated with medical management) still have an 8 percent 30 day mortality.

VIDEO - What is New in the Treatment of Type B Aortic Dissection?, Girma Tefera, MD, speaks at the University of Wisconsin School of Medicine and Public Health.

References

  1. Suzuki T, Mehta RR, Ince H, Nagai R, Sakomura Y, Weber F, Sumiyoshi T, Bossone E, Trimarchi S, Cooper J, Smith D, Isselbacher E, Eagle K, Nienaber C. "Clinical profiles and outcomes of acute type B aortic dissection in the current era: lessons from the International Registry of Aortic Dissection (IRAD)". Circulation. 108 Suppl 1: II312–7. PMID 12970252.

Acknowledgements

The content on this page was first contributed by: David Feller-Kopman, MD and C. Michael Gibson M.S., M.D. Template:WH Template:WS CME Category::Cardiology