Antianalgesia

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Antianalgesia is the ability of some endogenous chemicals (notably cholecystokinin and neuropeptide Y) to counter the effects of exogenous analgesics (such as morphine) or endogenous pain inhibiting neurotransmitters/modulators, such as the endogenous opioids. A learned form can be established using methods similar to the learning principle of conditioned inhibition, and has been demonstrated in rats.

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