Acinic cell carcinoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]

Overview

In western countries, salivary gland carcinomas account for 4000 out of 100000 of all head and neck carcinomas, and approximately 80% of those occurring in parotid gland. one out of six parotid gland cancer is acinic cell carcinoma. Distribution of acinic cell carcinoma between age groups seems to be quiet even, with a median age of 52 years, but it occurs mostly at a younger age. Children are rarely affected with salivary gland carcinoma, but if they are , it is most likely to be acinic cell carcinoma. Acinic cell carcinoma is predominantly seen in in whites (85000 out of 100000 cases) and less in African nations(8000 out of 100000 cases)here is a higher incidence among female with the ratio ranging from 1.43:1 to 1.57:1.

Epidemiology and Demographics

Prevalence

Age

Race

  • Acinic cell carcinoma is predominantly seen in in whites (85000 out of 100000 cases) and less in African nations(8000 out of 100000 cases)[5]

Gender

  • There is a higher incidence among female with the ratio ranging from 1.43:1 to 1.57:1.[6]

Region

  • There is no report about regional difference in acinic cell carcinoma.[7]

References

  1. Vander Poorten, V.; Triantafyllou, A.; Thompson, L. D. R.; Bishop, J.; Hauben, E.; Hunt, J.; Skalova, A.; Stenman, G.; Takes, R. P.; Gnepp, D. R.; Hellquist, H.; Wenig, B.; Bell, D.; Rinaldo, A.; Ferlito, A. (2015). "Salivary acinic cell carcinoma: reappraisal and update". European Archives of Oto-Rhino-Laryngology. 273 (11): 3511–3531. doi:10.1007/s00405-015-3855-7. ISSN 0937-4477.
  2. Al-Mamgani, Abrahim; van Rooij, Peter; Verduijn, Gerda M.; Meeuwis, Cees A.; Levendag, Peter C. (2012). "Long-term Outcomes and Quality of Life of 186 Patients With Primary Parotid Carcinoma Treated With Surgery and Radiotherapy at the Daniel den Hoed Cancer Center". International Journal of Radiation Oncology*Biology*Physics. 84 (1): 189–195. doi:10.1016/j.ijrobp.2011.11.045. ISSN 0360-3016.
  3. Neskey, David M.; Klein, Jonah D.; Hicks, Stephanie; Garden, Adam S.; Bell, Diana M.; El-Naggar, Adel K.; Kies, Merrill S.; Weber, Randal S.; Kupferman, Michael E. (2013). "Prognostic Factors Associated With Decreased Survival in Patients With Acinic Cell Carcinoma". JAMA Otolaryngology–Head & Neck Surgery. 139 (11): 1195. doi:10.1001/jamaoto.2013.4728. ISSN 2168-6181.
  4. Khosravi, Mohammad Hossein; Bagherihagh, Ali; Saeedi, Masoumeh; Dabirmoghaddam, Payman; Kouhi, Ali; Amirzade-Iranaq, Mohammad Hosein (2017). "Salivary Gland Cancers: A Survey through History, Classifications and Managements". doi:10.5772/intechopen.70127.
  5. Gomez, Daniel R.; Katabi, Nora; Zhung, Joanne; Wolden, Suzanne L.; Zelefsky, Michael J.; Kraus, Dennis H.; Shah, Jatin P.; Wong, Richard J.; Ghossein, Ronald A.; Lee, Nancy Y. (2009). "Clinical and pathologic prognostic features in acinic cell carcinoma of the parotid gland". Cancer. 115 (10): 2128–2137. doi:10.1002/cncr.24259. ISSN 0008-543X.
  6. Hoffman HT, Karnell LH, Robinson RA, Pinkston JA, Menck HR (1999). "National Cancer Data Base report on cancer of the head and neck: acinic cell carcinoma". Head Neck. 21 (4): 297–309. PMID 10376748.
  7. Neskey, David M.; Klein, Jonah D.; Hicks, Stephanie; Garden, Adam S.; Bell, Diana M.; El-Naggar, Adel K.; Kies, Merrill S.; Weber, Randal S.; Kupferman, Michael E. (2013). "Prognostic Factors Associated With Decreased Survival in Patients With Acinic Cell Carcinoma". JAMA Otolaryngology–Head & Neck Surgery. 139 (11): 1195. doi:10.1001/jamaoto.2013.4728. ISSN 2168-6181.

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