4,5-MDO-DMT, or 4,5-methylenedioxy-N,N-dimethyltryptamine, is a lesser-known psychedelic drug. It is the 4,5-methylenedioxy analog of DMT. 4,5-MDO-DMT was first synthesized by Alexander Shulgin. In his book TiHKAL (Tryptamines I Have Known and Loved), 4,5-MDO-DMT produces few to no noticeable psychoactive effects. Very little data exists about the pharmacological properties, metabolism, and toxicity of 4,5-MDO-DMT.