3-oxoacyl-(acyl-carrier-protein) reductase (NADH)

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In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) (EC 1.1.1.212) is an enzyme that catalyzes the chemical reaction

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NAD+ 3-oxoacyl-[acyl-carrier-protein] + NADH + H+

Thus, the two substrates of this enzyme are [[(3R)-3-hydroxyacyl-[acyl-carrier-protein]]] and NAD+, whereas its 3 products are [[3-oxoacyl-[acyl-carrier-protein]]], NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NAD+ oxidoreductase. Other names in common use include 3-oxoacyl-[acyl carrier protein] (reduced nicotinamide adenine, dinucleotide) reductase, and 3-oxoacyl-[acyl-carrier-protein] reductase (NADH).

References

  • IUBMB entry for 1.1.1.212
  • BRENDA references for 1.1.1.212 (Recommended.)
  • PubMed references for 1.1.1.212
  • PubMed Central references for 1.1.1.212
  • Google Scholar references for 1.1.1.212
  • Caughey I, Kekwick RG (1982). "The characteristics of some components of the fatty acid synthetase system in the plastids from the mesocarp of avocado (Persea americana) fruit". Eur. J. Biochem. 123: 553&ndash, 61. PMID 7075600.

External links

The CAS registry number for this enzyme class is 82047-86-7.

Gene Ontology (GO) codes


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