3-methylquercetin 7-O-methyltransferase

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In enzymology, a 3-methylquercetin 7-O-methyltransferase (EC is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 5,7,3',4'-tetrahydroxy-3-methoxyflavone S-adenosyl-L-homocysteine + 5,3',4'-trihydroxy-3,7-dimethoxyflavone

Thus, the two substrates of this enzyme are S-adenosyl methionine and 5,7,3',4'-tetrahydroxy-3-methoxyflavone, whereas its two products are S-adenosylhomocysteine and 5,3',4'-trihydroxy-3,7-dimethoxyflavone.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase. Other names in common use include flavonol 7-O-methyltransferase, flavonol 7-methyltransferase, 7-OMT, S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone, 7-O-methyltransferase, and 3-methylquercitin 7-O-methyltransferase [mis-spelt].


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  • De Luca V, Ibrahim RK (1985). "Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4'-O-methyltransferases". Arch. Biochem. Biophys. 238: 596&ndash, 605. PMID 3994393.

External links

The CAS registry number for this enzyme class is 96477-62-2.

Gene Ontology (GO) codes