3-Aminopyridine

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3-Aminopyridine

File:3-aminopyridine.svg
Names
IUPAC name Pyridin-3-amine
Other names 3-Pyridinamine; 3-Pyridylamine
Identifiers
CAS Number	462-08-8 N
3D model (JSmol)	Interactive image
ChemSpider	9615 Y
ECHA InfoCard
PubChem CID	10009
SMILES C1=CC(=CN=C1)N
Properties
Chemical formula	C5H6N2
Molar mass	94.12 g·mol−1
Hazards
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Overview

3-Aminopyridine is an aminopyridine. It can be used in the synthesis of organic ligand 3-pyridylnicotinamide

Preparation

3-Aminopyridine can be prepared by heating nicotinamide with sodium hypobromite which is in turn prepared in situ by the reaction of sodium hydroxide and bromine at 70 °C.

File:Synthesis of 3-Aminopyridine.gif

Toxicology

3-Aminopyridine can easily be absorbed through the skin. It is fatal if swallowed or absorbed through the skin. High concentrations can be extremely destructive to the tissues of mucous membranes and upper respiratory tract eyes and skin. Symptoms may also include convulsions and death. It also causes damage to the nervous system. Thermal decomposition leads to evolution of toxic gases such as carbon monoxide and oxides of nitrogen.