1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase

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In enzymology, a 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase (EC 2.6.1.56) is an enzyme that catalyzes the chemical reaction

1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine

Thus, the two substrates of this enzyme are 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol and pyruvate, whereas its two products are 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol and L-alanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol:pyruvate aminotransferase. Other names in common use include guanidinoaminodideoxy-scyllo-inositol-pyruvate aminotransferase, and L-alanine-N-amidino-3-(or 5-)keto-scyllo-inosamine transaminase.

References

  • IUBMB entry for 2.6.1.56
  • BRENDA references for 2.6.1.56 (Recommended.)
  • PubMed references for 2.6.1.56
  • PubMed Central references for 2.6.1.56
  • Google Scholar references for 2.6.1.56
  • Walker JB (1971). "Enzymatic reactions involved in streptomycin biosynthesis and metabolism". Lloydia. 34: 363&ndash, 71. PMID 4376579.
  • Walker JB, Walker MS (1969). "Streptomycin biosynthesis. Transamination reactions involving inosamines and inosadiamines". Biochemistry. 8: 763&ndash, 70. PMID 5781017.

External links

The CAS registry number for this enzyme class is 57127-19-2.

Gene Ontology (GO) codes


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