10-hydroxydihydrosanguinarine 10-O-methyltransferase

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In enzymology, a 10-hydroxydihydrosanguinarine 10-O-methyltransferase (EC 2.1.1.119) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine S-adenosyl-L-homocysteine + dihydrochelirubine

Thus, the two substrates of this enzyme are S-adenosyl methionine and 10-hydroxydihydrosanguinarine, whereas its two products are S-adenosylhomocysteine and dihydrochelirubine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.

References

  • IUBMB entry for 2.1.1.119
  • BRENDA references for 2.1.1.119 (Recommended.)
  • PubMed references for 2.1.1.119
  • PubMed Central references for 2.1.1.119
  • Google Scholar references for 2.1.1.119
  • De-Eknamkul W, Tanahashi T and Zenk MH (1992). "Enzymic 10-hydroxylation and 10-O-methylation of dihydrosanguinarine in dihydrochelirubine formation by Eschscholtzia". Phytochemistry. 31: 2713&ndash, 2717.

External links

The CAS registry number for this enzyme class is 144388-39-6.

Gene Ontology (GO) codes


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