Zollinger-Ellison syndrome classification: Difference between revisions
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==Overview== | ==Overview== | ||
*The World Health Organization classifies NETs into two broad categories, well differentiated and poorly differentiated, and most gastrinomas are considered well-differentiated NETs on the basis of histopathological analysis. | *The World Health Organization classifies [[neuroendocrine tumors]] (NETs) into two broad categories, well differentiated and poorly differentiated, and most [[Gastrinoma|gastrinomas]] are considered well-differentiated [[neuroendocrine tumors]] (NETs) on the basis of [[histopathological]] analysis. | ||
==Classiffication== | ==Classiffication== | ||
*Gastrinomas are derived from the [[enteroendocrine cells]] that arise from the embryologic endoderm, and form tumors mainly in the pancreas, but also in the proximal small intestine. Because of their origin, these are generally classified under the larger umbrella term of [[neuroendocrine tumors]] (NETs). <ref name="pmid7904550">{{cite journal |vauthors=Norton JA |title=Neuroendocrine tumors of the pancreas and duodenum |journal=Curr Probl Surg |volume=31 |issue=2 |pages=77–156 |year=1994 |pmid=7904550 |doi= |url=}}</ref> | *Gastrinomas are derived from the [[enteroendocrine cells]] that arise from the [[embryologic]] [[endoderm]], and form tumors mainly in the [[pancreas]], but also in the proximal [[small intestine]]. Because of their origin, these are generally classified under the larger umbrella term of [[neuroendocrine tumors]] (NETs). <ref name="pmid7904550">{{cite journal |vauthors=Norton JA |title=Neuroendocrine tumors of the pancreas and duodenum |journal=Curr Probl Surg |volume=31 |issue=2 |pages=77–156 |year=1994 |pmid=7904550 |doi= |url=}}</ref> | ||
*The World Health Organization classifies NETs into two broad categories, well differentiated and poorly differentiated, and most gastrinomas are considered well-differentiated NETs on the basis of histopathological analysis. It has been observed that most gastrinomas arise in the duodenum, with tumors located in the pancreas carrying greater malignant potential. <ref name="pmid23582915">{{cite journal| author=O'Toole D, Delle Fave G, Jensen RT| title=Gastric and duodenal neuroendocrine tumours. | journal=Best Pract Res Clin Gastroenterol | year= 2012 | volume= 26 | issue= 6 | pages= 719-35 | pmid=23582915 | doi=10.1016/j.bpg.2013.01.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23582915 }} </ref> | *The World Health Organization classifies [[neuroendocrine tumors]] (NETs) into two broad categories, well differentiated and poorly differentiated, and most [[Gastrinoma|gastrinomas]] are considered well-differentiated [[neuroendocrine tumors]] (NETs) on the basis of histopathological analysis. It has been observed that most [[Gastrinoma|gastrinomas]] arise in the duodenum, with tumors located in the [[pancreas]] carrying greater [[malignant]] potential. <ref name="pmid23582915">{{cite journal| author=O'Toole D, Delle Fave G, Jensen RT| title=Gastric and duodenal neuroendocrine tumours. | journal=Best Pract Res Clin Gastroenterol | year= 2012 | volume= 26 | issue= 6 | pages= 719-35 | pmid=23582915 | doi=10.1016/j.bpg.2013.01.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23582915 }} </ref> | ||
==References== | ==References== | ||
Revision as of 17:00, 1 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]
Overview
- The World Health Organization classifies neuroendocrine tumors (NETs) into two broad categories, well differentiated and poorly differentiated, and most gastrinomas are considered well-differentiated neuroendocrine tumors (NETs) on the basis of histopathological analysis.
Classiffication
- Gastrinomas are derived from the enteroendocrine cells that arise from the embryologic endoderm, and form tumors mainly in the pancreas, but also in the proximal small intestine. Because of their origin, these are generally classified under the larger umbrella term of neuroendocrine tumors (NETs). [1]
- The World Health Organization classifies neuroendocrine tumors (NETs) into two broad categories, well differentiated and poorly differentiated, and most gastrinomas are considered well-differentiated neuroendocrine tumors (NETs) on the basis of histopathological analysis. It has been observed that most gastrinomas arise in the duodenum, with tumors located in the pancreas carrying greater malignant potential. [2]
References
- ↑ Norton JA (1994). "Neuroendocrine tumors of the pancreas and duodenum". Curr Probl Surg. 31 (2): 77–156. PMID 7904550.
- ↑ O'Toole D, Delle Fave G, Jensen RT (2012). "Gastric and duodenal neuroendocrine tumours". Best Pract Res Clin Gastroenterol. 26 (6): 719–35. doi:10.1016/j.bpg.2013.01.002. PMID 23582915.