WBR1056

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Author [[PageAuthor::Abdurahman Khalil, M.D. [1]]]
Exam Type ExamType::USMLE Step 2 CK
Main Category MainCategory::Internal medicine, MainCategory::OB/GYN
Sub Category SubCategory::Genitourinary, SubCategory::Infectious Disease
Prompt [[Prompt::A 32 year old woman G1P1 comes to the clinic complaining of urgency, frequency and burning during urination for the last 4 days. She never had this problem before. She denies any fever, night sweating or pain. Her past medical history unremarkable except for caesarian section 3 years ago. She doesn’t smoke, drinks alcohol occasionally and sexually active with her husband, her vitals are Temperature: 37, 1 , heart rate: 78 , respiration: 17, blood pressure: 134/67. The physical examination is normal except for mild tenderness over the pubic area. Tapping on Costco vertebral angel doesn’t show any tenderness. No

vaginal discharge. What’s the preferred treatment for this patient?]]

Answer A AnswerA::Nitrofurantoin
Answer A Explanation AnswerAExp::Correct, nitrofurantoin is the preferred antibacterial to treat acute cystitis.
Answer B AnswerB::Ciprofloxacin
Answer B Explanation AnswerBExp::Incorrect. Broad spectrum antibiotics are reserved for intolerance or failure of first line antibacterials.
Answer C AnswerC::Ceftriaxone
Answer C Explanation AnswerCExp::Incorrect. Beta-lactams is not recommended because of the increasing resistance, in addition to their adverse effects and poor efficacy.
Answer D AnswerD::Doxycycline
Answer D Explanation AnswerDExp::Incorrect. Doxycycline is used to treat chlamydiae, but is not as effective to treat e.coli which is the most common cause of simple cystitis.
Answer E AnswerE::Erythromycin
Answer E Explanation AnswerEExp::Incorrect. not effective to treat acute cystitis.
Right Answer RightAnswer::A
Explanation [[Explanation::

Educational Objective:
References: IDSA guidelines for acute cystitis.[1]]]

Approved Approved::No
Keyword WBRKeyword::Cystitis, WBRKeyword::E.coli, WBRKeyword::Antibiotic resistance
Linked Question Linked::
Order in Linked Questions LinkedOrder::
  1. Gupta K, Hooton TM, Naber KG, Wullt B, Colgan R, Miller LG; et al. (2011). "International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases". Clin Infect Dis. 52 (5): e103–20. doi:10.1093/cid/ciq257. PMID 21292654.