WBR0997

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Author [[PageAuthor::Mohamed Moubarak, M.D. [1]]]
Exam Type ExamType::USMLE Step 3
Main Category MainCategory::Emergency Room
Sub Category SubCategory::Cardiovascular
Prompt [[Prompt::A 62 year-old man comes to ED complaining of acute shortness of breath, fatigue, and worsening exertional dyspnea. He hardly can talk, and mentioned waking up several times at night on sever cough with frothy sputum. He used to sleep on two pillows but now he is using three. The patient has past medical history of hypertension for 15 years, and diabetes mellitus for 20 years. On examination, his BP 90/70, pulse 120, respiratory rate 28, and temperature is 36.9 C (98.5F). Chest examination revealed decreased breath sounds and dullness at both bases with bibasilar rales. Cardiac examination revealed diffuse, laterally and inferiorly displaced apex, with distant heart sounds and S3 gallop. There is a jugular venous distention, with JVP of 12 cm, and oxygen saturation of 83%. Extremities are cool and show 2+ pitting edema in both legs up to the knees. Which test would be most sensitive for the diagnosis of this condition?]]
Answer A AnswerA::CK-MB
Answer A Explanation [[AnswerAExp::Incorrect

Cardiac enzymes are neither sensitive nor specific for CHF diagnosis]]

Answer B AnswerB::LDH
Answer B Explanation [[AnswerBExp::Incorrect

Cardiac enzymes are neither sensitive nor specific for CHF diagnosis]]

Answer C AnswerC::brain natriuretic peptide (BNP)
Answer C Explanation [[AnswerCExp::Correct

BNP test has been found to be both sensitive and specific for the diagnosis of CHF]]

Answer D AnswerD::Chest x-ray
Answer D Explanation [[AnswerDExp::Incorrect

Chest x-ray can determine the presence of pulmonary edema but not its cause.]]

Answer E AnswerE::Troponin I
Answer E Explanation [[AnswerEExp::Incorrect

Cardiac enzymes are neither sensitive nor specific for CHF diagnosis]]

Right Answer RightAnswer::C
Explanation [[Explanation::The BNP test has been found to be both sensitive and specific for the diagnosis of CHF. It can be a very useful test to order when a patient is dyspneic to help to determine if CHF is the cause. Troponin, CK-MB, and LDH are markers of damage to cardiac muscle. Cardiac enzymes are neither sensitive nor specific for CHF. Similarly, a CXR can determine the presence of pulmonary edema but not its cause.

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Approved Approved::No
Keyword [[WBRKeyword::Pulmonary edema]]
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