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[[Image:WBR0846.jpg|500px]]
[[Image:WBR0846.jpg|500px]]
|Explanation=The image shown above is that of ''Staphylococcus aureus''. ''S. aureus'' is a gram-positive (violet color on gram-stain) coccus (circular shape) organized in clusters that resemble grapes. In fact, the Greek word "staphyle" means "grape". Staphylococcus aureus classically colonizes the anterior nares. Approximately 30-50% of individuals carry S. aureus in the anterior nares and are completely healthy. Other sites of S. aureus are also possible, such as in the throat.  
|Explanation=The image shown above is that of ''Staphylococcus aureus''. ''S. aureus'' is a gram-positive (violet color on gram-stain) coccus (circular shape) organized in clusters that resemble grapes. In fact, the Greek word "staphyle" means "grape". Staphylococcus aureus classically colonizes the anterior nares. Approximately 30-50% of individuals carry S. aureus in the anterior nares and are completely healthy. Other sites of S. aureus are also possible, such as in the throat.
|AnswerA=Rectum
|AnswerA=Rectum
|AnswerAExp=Several organisms, such as Lactobacilli, can colonize the rectum.
|AnswerAExp=Several organisms, such as Lactobacilli, can colonize the rectum.
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|EducationalObjectives=''Staphylococcus aureus'' are gram-positive cocci that are arranged in clusters. The classical site of primary colonization is the anterior nares.
|EducationalObjectives=''Staphylococcus aureus'' are gram-positive cocci that are arranged in clusters. The classical site of primary colonization is the anterior nares.
|References=Hu L, Umeda A, Kondo S, et al. Typing of Staphylococcus aureus colonising human nasal carriers by pulsed-field gel electrophoresis. J Med Microbiol. 1995; 42(2):127-32.
|References=Hu L, Umeda A, Kondo S, et al. Typing of Staphylococcus aureus colonising human nasal carriers by pulsed-field gel electrophoresis. J Med Microbiol. 1995; 42(2):127-32.
Image attribution: Bobjgalindo. 2005. This file is licensed under the Creative Commons Attribution-Share Alike 3.0 license.
|RightAnswer=D
|RightAnswer=D
|WBRKeyword=Staphylococcus, Staphylococcal, Anterior nares, Colonization, Culture, Swab, Gram-positive, Cocci, Coccus
|WBRKeyword=Staphylococcus, Staphylococcal, Anterior nares, Colonization, Culture, Swab, Gram-positive, Cocci, Coccus
|Approved=Yes
|Approved=Yes
}}
}}

Revision as of 23:14, 4 March 2015

 
Author [[PageAuthor::Yazan Daaboul, M.D. (Reviewed by Serge Korjian)]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Microbiology
Sub Category SubCategory::General Principles
Prompt [[Prompt::In an experiment, a researcher obtains swab samples from 50 asymptomatic volunteers to detect the possible bacterial species that colonize uninfected individuals. He isolates several species and records his findings. Despite a significant similarily between recovered species, the growth of the bacteria shown in the image below was noted in approximately 25% of his subjects. Which of the following is most likely the site of colonization of the cultured organism?

]]

Answer A AnswerA::Rectum
Answer A Explanation AnswerAExp::Several organisms, such as Lactobacilli, can colonize the rectum.
Answer B AnswerB::Oral cavity
Answer B Explanation AnswerBExp::Anaerobes, such as ''Actinomyces israelii'' colonize the oral cavity.
Answer C AnswerC::Vagina
Answer C Explanation AnswerCExp::Several organisms, such as Lactobacilli, can colonize the vagina.
Answer D AnswerD::Anterior nares
Answer D Explanation AnswerDExp::''Staphylococcus aureus'' colonizes the anterior nares.
Answer E AnswerE::Nasopharynx
Answer E Explanation AnswerEExp::Several bacteria can colonize the nasopharynx, such as Neisseria species, ''H. influenzae'' type B, ''M. catarrhalis'', and ''S. pneumoniae''.
Right Answer RightAnswer::D
Explanation [[Explanation::The image shown above is that of Staphylococcus aureus. S. aureus is a gram-positive (violet color on gram-stain) coccus (circular shape) organized in clusters that resemble grapes. In fact, the Greek word "staphyle" means "grape". Staphylococcus aureus classically colonizes the anterior nares. Approximately 30-50% of individuals carry S. aureus in the anterior nares and are completely healthy. Other sites of S. aureus are also possible, such as in the throat.

Educational Objective: Staphylococcus aureus are gram-positive cocci that are arranged in clusters. The classical site of primary colonization is the anterior nares.
References: Hu L, Umeda A, Kondo S, et al. Typing of Staphylococcus aureus colonising human nasal carriers by pulsed-field gel electrophoresis. J Med Microbiol. 1995; 42(2):127-32. Image attribution: Bobjgalindo. 2005. This file is licensed under the Creative Commons Attribution-Share Alike 3.0 license.]]

Approved Approved::Yes
Keyword WBRKeyword::Staphylococcus, WBRKeyword::Staphylococcal, WBRKeyword::Anterior nares, WBRKeyword::Colonization, WBRKeyword::Culture, WBRKeyword::Swab, WBRKeyword::Gram-positive, WBRKeyword::Cocci, WBRKeyword::Coccus
Linked Question Linked::
Order in Linked Questions LinkedOrder::