WBR0804: Difference between revisions
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|QuestionAuthor=[[User:Gonzalo Romero|Gonzalo A. Romero, M.D.]] [mailto:gromero@wikidoc.org] | |QuestionAuthor=[[User:Gonzalo Romero|Gonzalo A. Romero, M.D.]] [mailto:gromero@wikidoc.org] | ||
|ExamType=USMLE Step 1 | |ExamType=USMLE Step 1 | ||
|MainCategory=Pathology | |MainCategory=Pathology | ||
|SubCategory= | |SubCategory=Dermatology | ||
|MainCategory=Pathology | |MainCategory=Pathology | ||
|SubCategory= | |SubCategory=Dermatology | ||
|MainCategory=Pathology | |MainCategory=Pathology | ||
|SubCategory= | |SubCategory=Dermatology | ||
|MainCategory=Pathology | |MainCategory=Pathology | ||
|MainCategory=Pathology | |MainCategory=Pathology | ||
|SubCategory= | |SubCategory=Dermatology | ||
|MainCategory=Pathology | |MainCategory=Pathology | ||
|SubCategory= | |SubCategory=Dermatology | ||
|MainCategory=Pathology | |MainCategory=Pathology | ||
|SubCategory= | |SubCategory=Dermatology | ||
|MainCategory=Pathology | |MainCategory=Pathology | ||
|SubCategory= | |SubCategory=Dermatology | ||
|MainCategory=Pathology | |MainCategory=Pathology | ||
|MainCategory=Pathology | |MainCategory=Pathology | ||
|SubCategory= | |SubCategory=Dermatology | ||
|Prompt=A 68-year-old man comes to the clinic complaining of an ulcer on his face. He has been a sailor for his entire life. It is indolent in nature. The patient states that it has been growing slowly over the past 9 months. On physical exam it is clean looking, has 2 cm in diameter and is located on the lower lip. There are no lymphadenopathies in the head or neck. A surgeon performs an excision with clear margins. The pathologist finds epithelized cells in concentric fashion with a focus of central keratinization on the microscope. Which of the following risk factors and types of cancer has similar findings on the microscope? | |Prompt=A 68-year-old man comes to the clinic complaining of an ulcer on his face. He has been a sailor for his entire life. It is indolent in nature. The patient states that it has been growing slowly over the past 9 months. On physical exam it is clean looking, has 2 cm in diameter and is located on the lower lip. There are no lymphadenopathies in the head or neck. A surgeon performs an excision with clear margins. The pathologist finds epithelized cells in concentric fashion with a focus of central keratinization on the microscope. Which of the following risk factors and types of cancer has similar findings on the microscope? | ||
|Explanation= | |Explanation= | ||
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|AnswerAExp=<font color="Green">'''Correct.'''</font> See overall explanation | |AnswerAExp=<font color="Green">'''Correct.'''</font> See overall explanation | ||
|AnswerB=Alcohol - adenocarcinoma of the esophagus | |AnswerB=Alcohol - adenocarcinoma of the esophagus | ||
|AnswerBExp=<font color="red">'''Incorrect.'''</font> Alcohol consumption | |AnswerBExp=<font color="red">'''Incorrect.'''</font> Alcohol consumption and smoking are associated with squamous cell carcinoma of the esophagus. Adenocarcinomas are often associated with a history of gastroesophageal reflux disease and Barrett's esophagus. | ||
|AnswerC=Cocaine - septal nasal perforation | |AnswerC=Cocaine - septal nasal perforation | ||
|AnswerCExp=<font color="red">'''Incorrect.'''</font> This association is correct, but does not cause the the changes found on light microscopy. Cocaine causes vasoconstriction which limits the blood flow causing ischemic necrosis and nasal septum perforation. | |AnswerCExp=<font color="red">'''Incorrect.'''</font> This association is correct, but does not cause the the changes found on light microscopy. Cocaine causes vasoconstriction which limits the blood flow causing ischemic necrosis and nasal septum perforation. | ||
|AnswerD=Low fiber diet - adenocarcinoma of the colon | |AnswerD=Low fiber diet - adenocarcinoma of the colon | ||
|AnswerDExp=<font color="red">'''Incorrect.'''</font> High fiber diet, particularly cereal and whole grains, can absorb carcinogens from the diet decreasing colorectal cancer risk. | |AnswerDExp=<font color="red">'''Incorrect.'''</font> High fiber diet, particularly cereal and whole grains, can absorb carcinogens from the diet decreasing colorectal cancer risk. | ||
|AnswerE=Smoking - bronchogenic adenocarcinoma | |AnswerE=Smoking - bronchogenic adenocarcinoma | ||
|AnswerEExp=<font color="red">'''Incorrect.'''</font> | |AnswerEExp=<font color="red">'''Incorrect.'''</font> Smoking is associate with higher risk of developing bronchogenic adenocarcinoma. Its histologic findings correspond to malignant mucin producing cells (glands). | ||
|RightAnswer=A | |RightAnswer=A | ||
|WBRKeyword=skin cancer, Squamous cell carcinoma, keratin pearls | |WBRKeyword=skin cancer, Squamous cell carcinoma, keratin pearls | ||
|Approved=No | |Approved=No | ||
}} | }} | ||
Revision as of 19:09, 15 October 2013
| Author | [[PageAuthor::Gonzalo A. Romero, M.D. [1]]] |
|---|---|
| Exam Type | ExamType::USMLE Step 1 |
| Main Category | MainCategory::Pathology |
| Sub Category | SubCategory::Dermatology |
| Prompt | [[Prompt::A 68-year-old man comes to the clinic complaining of an ulcer on his face. He has been a sailor for his entire life. It is indolent in nature. The patient states that it has been growing slowly over the past 9 months. On physical exam it is clean looking, has 2 cm in diameter and is located on the lower lip. There are no lymphadenopathies in the head or neck. A surgeon performs an excision with clear margins. The pathologist finds epithelized cells in concentric fashion with a focus of central keratinization on the microscope. Which of the following risk factors and types of cancer has similar findings on the microscope?]] |
| Answer A | AnswerA::Smoking - squamous cell carcinoma of the esophagus |
| Answer A Explanation | [[AnswerAExp::Correct. See overall explanation]] |
| Answer B | AnswerB::Alcohol - adenocarcinoma of the esophagus |
| Answer B Explanation | [[AnswerBExp::Incorrect. Alcohol consumption and smoking are associated with squamous cell carcinoma of the esophagus. Adenocarcinomas are often associated with a history of gastroesophageal reflux disease and Barrett's esophagus.]] |
| Answer C | AnswerC::Cocaine - septal nasal perforation |
| Answer C Explanation | [[AnswerCExp::Incorrect. This association is correct, but does not cause the the changes found on light microscopy. Cocaine causes vasoconstriction which limits the blood flow causing ischemic necrosis and nasal septum perforation.]] |
| Answer D | AnswerD::Low fiber diet - adenocarcinoma of the colon |
| Answer D Explanation | [[AnswerDExp::Incorrect. High fiber diet, particularly cereal and whole grains, can absorb carcinogens from the diet decreasing colorectal cancer risk.]] |
| Answer E | AnswerE::Smoking - bronchogenic adenocarcinoma |
| Answer E Explanation | [[AnswerEExp::Incorrect. Smoking is associate with higher risk of developing bronchogenic adenocarcinoma. Its histologic findings correspond to malignant mucin producing cells (glands).]] |
| Right Answer | RightAnswer::A |
| Explanation | [[Explanation::Educational Objective:
Educational Objective: |
| Approved | Approved::No |
| Keyword | WBRKeyword::skin cancer, WBRKeyword::Squamous cell carcinoma, WBRKeyword::keratin pearls |
| Linked Question | Linked:: |
| Order in Linked Questions | LinkedOrder:: |