WBR0660

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Author [[PageAuthor::Rim Halaby, M.D. [1]]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Biostatistics/ Epidemiology
Sub Category SubCategory::Gastrointestinal
Prompt [[Prompt::A new vaccine is being developed for the prevention of Hepatitis E. In phase 3 of the clinical trial, a group of 100 people is randomized to receive either the vaccine or placebo. Out of the 50 patients that received the vaccine 1 went on to develop Hepatitis E in the 6 month follow up after the vaccination. In the placebo group 7 out of 50 patients developed Hepatitis. What is the number needed to treat for this newly developed vaccine according to the results of this trial?]]
Answer A AnswerA::0.14
Answer A Explanation AnswerAExp::
Answer B AnswerB::7.14
Answer B Explanation AnswerBExp::
Answer C AnswerC::8.33
Answer C Explanation AnswerCExp::
Answer D AnswerD::300
Answer D Explanation AnswerDExp::
Answer E AnswerE::Data insufficient to calculate
Answer E Explanation AnswerEExp::
Right Answer RightAnswer::C
Explanation [[Explanation::The number needed to treat refers to the number of patients required to receive a certain treatment for 1 patient to benefit from it. It is usually the inverse of the absolute risk reduction(ARR). The ARR can be calculated as follows:


Educational objective: The number needed to treat is calculated by finding the inverse of the absolute risk reduction (1/ARR)
Educational Objective:
References: ]]

Approved Approved::No
Keyword WBRKeyword::Number needed to treat
Linked Question Linked::
Order in Linked Questions LinkedOrder::