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|QuestionAuthor=[[User:Gonzalo Romero|Gonzalo A. Romero, M.D.]] [mailto:gromero@wikidoc.org] | |QuestionAuthor=[[User:Gonzalo Romero|Gonzalo A. Romero, M.D.]] [mailto:gromero@wikidoc.org] | ||
|ExamType=USMLE Step 2 CK | |ExamType=USMLE Step 2 CK | ||
|SubCategory=Endocrine | |||
|SubCategory=Endocrine | |SubCategory=Endocrine | ||
|SubCategory=Endocrine | |||
|SubCategory= | |SubCategory=Endocrine | ||
|SubCategory=Endocrine | |||
|SubCategory= | |SubCategory=Endocrine | ||
|SubCategory=Endocrine | |||
|SubCategory=Endocrine | |||
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|SubCategory=Endocrine | |||
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|Prompt=A 45-year-old female comes to the physician due to a 6-month history of difficulty swallowing. She is very worried because her condition is getting worse. At first, she thought it was a cold. Review of systems is significant for dyspnea and stridor. Upon examination her vitals are within normal limits, her neck is supple without JVD and her thyroid has a hard consistency and non-mobile. Her TSH and free T3 and T4 are within normal limits. A fine needle aspiration is performed on it shows dense collagenous replacement of the thyroid gland with chronic inflammation. Which of the following complications is this patient most likely to develop? | |Prompt=A 45-year-old female comes to the physician due to a 6-month history of difficulty swallowing. She is very worried because her condition is getting worse. At first, she thought it was a cold. Review of systems is significant for dyspnea and stridor. Upon examination her vitals are within normal limits, her neck is supple without JVD and her thyroid has a hard consistency and non-mobile. Her TSH and free T3 and T4 are within normal limits. A fine needle aspiration is performed on it shows dense collagenous replacement of the thyroid gland with chronic inflammation. Which of the following complications is this patient most likely to develop? | ||
|Explanation=This patient is presenting with symptoms and signs of [[Riedel's thyroiditis]], a chronic inflammatory disease of the [[thyroid]], which causes [[fibrosis]]. The fibrosis can extend to adjacent structures causing dysphagia, dyspnea, dysphonia and hoarseness (due to the laryngeal nerve involvement), [[hypoparathyroidism]]. 30% of patients present with [[hypothyroidism]], but most patients are euthyroid. | |Explanation=This patient is presenting with symptoms and signs of [[Riedel's thyroiditis]], a chronic inflammatory disease of the [[thyroid]], which causes [[fibrosis]]. The fibrosis can extend to adjacent structures causing dysphagia, dyspnea, dysphonia and hoarseness (due to the laryngeal nerve involvement), [[hypoparathyroidism]]. 30% of patients present with [[hypothyroidism]], but most patients are euthyroid. | ||
|AnswerA=Papillary carcinoma of the thyroid | |AnswerA=Papillary carcinoma of the thyroid | ||
|AnswerAExp= | |AnswerAExp=[[Thyroid cancer|Papillary carcinoma of the thyroid]] is the most common type of thyroid cancer 75 to 85% of cases of all thyroid cancers. Microscopically is seen as with the characteristic Orphan Anney eye nuclear inclusions (nuclei with uniform staining) and [[psammoma body]] (laminated concentric calcifications). | ||
|AnswerB=Retroperitoneal fibrosis | |AnswerB=Retroperitoneal fibrosis | ||
|AnswerBExp= | |AnswerBExp=[[Riedel's thyroiditis]] can involve mediastinal and retroperitoneal fibrosis. | ||
|AnswerC=Thyroid storm | |AnswerC=Thyroid storm | ||
|AnswerCExp= | |AnswerCExp=[[Thyroid storm]] is defined as a sudden elevation of the thyroid hormones. Riedel thyroiditis is not associated with thyroid storm. Contrary, it is associated with hypothyroidism. | ||
|AnswerD=Pneumonia | |AnswerD=Pneumonia | ||
|AnswerDExp= | |AnswerDExp=Although mediastinal fibrosis could potentially lead to peribronchial fibrosis, riedel thyroiditis is not commonly associated with [[pneumonia]]. | ||
|AnswerE=Thyroid lymphoma | |AnswerE=Thyroid lymphoma | ||
|AnswerEExp= | |AnswerEExp=Thyroid lymphoma is a rare complication of [[Hashimoto thyroiditis]]. | ||
|EducationalObjectives=Riedel thyroiditis can cause mediastinal and retroperitoneal fibrosis | |||
|References=First Aid 2014 page 321 | |||
|RightAnswer=B | |RightAnswer=B | ||
|WBRKeyword=Riedel thyroiditis | |WBRKeyword=Riedel thyroiditis, Thyroiditis, | ||
|Approved=Yes | |Approved=Yes | ||
}} | }} | ||
Revision as of 20:53, 14 September 2014
| Author | [[PageAuthor::Gonzalo A. Romero, M.D. [1]]] |
|---|---|
| Exam Type | ExamType::USMLE Step 2 CK |
| Main Category | |
| Sub Category | SubCategory::Endocrine |
| Prompt | [[Prompt::A 45-year-old female comes to the physician due to a 6-month history of difficulty swallowing. She is very worried because her condition is getting worse. At first, she thought it was a cold. Review of systems is significant for dyspnea and stridor. Upon examination her vitals are within normal limits, her neck is supple without JVD and her thyroid has a hard consistency and non-mobile. Her TSH and free T3 and T4 are within normal limits. A fine needle aspiration is performed on it shows dense collagenous replacement of the thyroid gland with chronic inflammation. Which of the following complications is this patient most likely to develop?]] |
| Answer A | AnswerA::Papillary carcinoma of the thyroid |
| Answer A Explanation | [[AnswerAExp::Papillary carcinoma of the thyroid is the most common type of thyroid cancer 75 to 85% of cases of all thyroid cancers. Microscopically is seen as with the characteristic Orphan Anney eye nuclear inclusions (nuclei with uniform staining) and psammoma body (laminated concentric calcifications).]] |
| Answer B | AnswerB::Retroperitoneal fibrosis |
| Answer B Explanation | [[AnswerBExp::Riedel's thyroiditis can involve mediastinal and retroperitoneal fibrosis.]] |
| Answer C | AnswerC::Thyroid storm |
| Answer C Explanation | [[AnswerCExp::Thyroid storm is defined as a sudden elevation of the thyroid hormones. Riedel thyroiditis is not associated with thyroid storm. Contrary, it is associated with hypothyroidism.]] |
| Answer D | AnswerD::Pneumonia |
| Answer D Explanation | [[AnswerDExp::Although mediastinal fibrosis could potentially lead to peribronchial fibrosis, riedel thyroiditis is not commonly associated with pneumonia.]] |
| Answer E | AnswerE::Thyroid lymphoma |
| Answer E Explanation | [[AnswerEExp::Thyroid lymphoma is a rare complication of Hashimoto thyroiditis.]] |
| Right Answer | RightAnswer::B |
| Explanation | [[Explanation::This patient is presenting with symptoms and signs of Riedel's thyroiditis, a chronic inflammatory disease of the thyroid, which causes fibrosis. The fibrosis can extend to adjacent structures causing dysphagia, dyspnea, dysphonia and hoarseness (due to the laryngeal nerve involvement), hypoparathyroidism. 30% of patients present with hypothyroidism, but most patients are euthyroid. Educational Objective: Riedel thyroiditis can cause mediastinal and retroperitoneal fibrosis |
| Approved | Approved::Yes |
| Keyword | WBRKeyword::Riedel thyroiditis, WBRKeyword::Thyroiditis |
| Linked Question | Linked:: |
| Order in Linked Questions | LinkedOrder:: |