Ventricular tachycardia epidemiology and demographics: Difference between revisions

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A Companion to Braunwald's heart disease'' (1st ed., pp. 393). Philadelphia, Pa: Saunders Elsevier.</ref>
A Companion to Braunwald's heart disease'' (1st ed., pp. 393). Philadelphia, Pa: Saunders Elsevier.</ref>


* However, the underlying substrate varies: [[ischemic heart disease]] in 75–80% cases; idiopathic [[cardiomyopathy]] in 10–15%; and 1–2% due to rare monogenic mutations in cardiac ion channels or associated proteins.4
* However, the underlying substrate varies: [[ischemic heart disease]] in 75–80% cases; idiopathic [[cardiomyopathy]] in 10–15%; and 1–2% due to rare monogenic mutations in cardiac ion channels or associated proteins.<ref> Zipes DP, Jalife J(2009). '' Cardiac electrophysiology: from cell to bedside '' (5th ed.). Philadelphia, Pa: Saunders Elsevier.</ref>


* [[Brugada Syndrome]] may account for up to 50% of all [[SCD]s in young individuals without structural heart disease. 4
* [[Brugada Syndrome]] may account for up to 50% of all [[SCD]s in young individuals without structural heart disease. <ref> Zipes DP, Jalife J(2009). '' Cardiac electrophysiology: from cell to bedside '' (5th ed.). Philadelphia, Pa: Saunders Elsevier.</ref>


* The prevalence of nonsustained [[VT]] detected by 24-hour Ambulatory ECGs was 4% in 98 elderly, disease-free individuals in the Baltimore Longitudinal Study of Aging,5 4% in 106 active elderly people,6 2% in 50 elderly people without cardiovascular disease,7 4% in 729 elderly women and 13% in 643 elderly men in the Cardiovascular Health Study,8 3% in 135 elderly men and 2% in 297 elderly women without cardiovascular disease,9 9% in 385 elderly men and 8% in 806 elderly women with hypertension, valvular disease, or cardiomyopathy,9 6% in 395 elderly men and 15% in 771 elderly women with coronary artery disease (CAD),9 and 5% in a well population of 80 year olds in the Bronx Longitudinal Aging Study.10
* The prevalence of nonsustained [[VT]] detected by 24-hour Ambulatory ECGs was 4% in 98 elderly, disease-free individuals in the Baltimore Longitudinal Study of Aging,<ref name="pmid7056104">{{cite journal| author=Fleg JL, Kennedy HL| title=Cardiac arrhythmias in a healthy elderly population: detection by 24-hour ambulatory electrocardiography. | journal=Chest | year= 1982 | volume= 81 | issue= 3 | pages= 302-7 | pmid=7056104 | doi= | pmc= | url= }} </ref> 4% in 106 active elderly people,<ref name="pmid7369099">{{cite journal| author=Camm AJ, Evans KE, Ward DE, Martin A| title=The rhythm of the heart in active elderly subjects. | journal=Am Heart J | year= 1980 | volume= 99 | issue= 5 | pages= 598-603 | pmid=7369099 | doi= | pmc= | url= }} </ref> 2% in 50 elderly people without cardiovascular disease,<ref name="pmid3946253">{{cite journal| author=Kantelip JP, Sage E, Duchene-Marullaz P| title=Findings on ambulatory electrocardiographic monitoring in subjects older than 80 years. | journal=Am J Cardiol | year= 1986 | volume= 57 | issue= 6 | pages= 398-401 | pmid=3946253 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3946253  }} </ref> 4% in 729 elderly women and 13% in 643 elderly men in the Cardiovascular Health Study,<ref name="pmid8106697">{{cite journal| author=Manolio TA, Furberg CD, Rautaharju PM, Siscovick D, Newman AB, Borhani NO et al.| title=Cardiac arrhythmias on 24-h ambulatory electrocardiography in older women and men: the Cardiovascular Health Study. | journal=J Am Coll Cardiol | year= 1994 | volume= 23 | issue= 4 | pages= 916-25 | pmid=8106697 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8106697  }} </ref> 3% in 135 elderly men and 2% in 297 elderly women without cardiovascular disease,<ref name="pmid11867655">{{cite journal| author=Aronow WS, Ahn C, Mercando AD, Epstein S, Kronzon I| title=Prevalence and association of ventricular tachycardia and complex ventricular arrhythmias with new coronary events in older men and women with and without cardiovascular disease. | journal=J Gerontol A Biol Sci Med Sci | year= 2002 | volume= 57 | issue= 3 | pages= M178-80 | pmid=11867655 | doi= | pmc= | url= }} </ref> 9% in 385 elderly men and 8% in 806 elderly women with hypertension, valvular disease, or cardiomyopathy,<ref name="pmid11867655">{{cite journal| author=Aronow WS, Ahn C, Mercando AD, Epstein S, Kronzon I| title=Prevalence and association of ventricular tachycardia and complex ventricular arrhythmias with new coronary events in older men and women with and without cardiovascular disease. | journal=J Gerontol A Biol Sci Med Sci | year= 2002 | volume= 57 | issue= 3 | pages= M178-80 | pmid=11867655 | doi= | pmc= | url= }} </ref> 6% in 395 elderly men and 15% in 771 elderly women with coronary artery disease (CAD),<ref name="pmid11867655">{{cite journal| author=Aronow WS, Ahn C, Mercando AD, Epstein S, Kronzon I| title=Prevalence and association of ventricular tachycardia and complex ventricular arrhythmias with new coronary events in older men and women with and without cardiovascular disease. | journal=J Gerontol A Biol Sci Med Sci | year= 2002 | volume= 57 | issue= 3 | pages= M178-80 | pmid=11867655 | doi= | pmc= | url= }} </ref> and 5% in a well population of 80 year olds in the Bronx Longitudinal Aging Study.<ref name="pmid9494777">{{cite journal| author=Frishman WH, Sokol S, Aronson MK, Wassertheil-Smoller S, Katzman R| title=Risk factors for cardiovascular and cerebrovascular diseases and dementia in the elderly. | journal=Curr Probl Cardiol | year= 1998 | volume= 23 | issue= 1 | pages= 1-62 | pmid=9494777 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9494777  }} </ref>


* The prevalence of complex ventricular arrhythmia in elderly people in these studies was 50%,5 31%,6 20%,7 16% in women and 28% in men,8 31% in men and 30% in women without cardiovascular disease,9 54% in men and 55% in women with hypertension, valvular disease, or cardiomyopathy,9 and 69% in men and 68% in women with CAD.9
* The prevalence of complex ventricular arrhythmia in elderly people in these studies was 50%,5 31%,6 20%,7 16% in women and 28% in men,<ref name="pmid11867655">{{cite journal| author=Aronow WS, Ahn C, Mercando AD, Epstein S, Kronzon I| title=Prevalence and association of ventricular tachycardia and complex ventricular arrhythmias with new coronary events in older men and women with and without cardiovascular disease. | journal=J Gerontol A Biol Sci Med Sci | year= 2002 | volume= 57 | issue= 3 | pages= M178-80 | pmid=11867655 | doi= | pmc= | url= }} </ref> 31% in men and 30% in women without cardiovascular disease,<ref name="pmid11867655">{{cite journal| author=Aronow WS, Ahn C, Mercando AD, Epstein S, Kronzon I| title=Prevalence and association of ventricular tachycardia and complex ventricular arrhythmias with new coronary events in older men and women with and without cardiovascular disease. | journal=J Gerontol A Biol Sci Med Sci | year= 2002 | volume= 57 | issue= 3 | pages= M178-80 | pmid=11867655 | doi= | pmc= | url= }} </ref> 54% in men and 55% in women with hypertension, valvular disease, or cardiomyopathy,<ref name="pmid11867655">{{cite journal| author=Aronow WS, Ahn C, Mercando AD, Epstein S, Kronzon I| title=Prevalence and association of ventricular tachycardia and complex ventricular arrhythmias with new coronary events in older men and women with and without cardiovascular disease. | journal=J Gerontol A Biol Sci Med Sci | year= 2002 | volume= 57 | issue= 3 | pages= M178-80 | pmid=11867655 | doi= | pmc= | url= }} </ref> and 69% in men and 68% in women with CAD.<ref name="pmid11867655">{{cite journal| author=Aronow WS, Ahn C, Mercando AD, Epstein S, Kronzon I| title=Prevalence and association of ventricular tachycardia and complex ventricular arrhythmias with new coronary events in older men and women with and without cardiovascular disease. | journal=J Gerontol A Biol Sci Med Sci | year= 2002 | volume= 57 | issue= 3 | pages= M178-80 | pmid=11867655 | doi= | pmc= | url= }} </ref>

Revision as of 07:17, 12 October 2011

  • Sustained ventricular tachycardia (VT) is an important cause of 150,000 to 300,000 out of hospital sudden deaths that occur annually in the US.[1]
  • The most common cause of wide complex tachycardia(WCT) is ventricular tachycardia (VT), which accounts for 80% of all cases of WCT.[2]
  • Supraventricular tachycardia (SVT) with aberrancy accounts for 15% to 20% of WCTs. SVTs with bystander preexcitation and antidromic atrioventricular reentrant tachycardia (AVRT) account for 1% to 6% of WCTs.[3]
  • However, the underlying substrate varies: ischemic heart disease in 75–80% cases; idiopathic cardiomyopathy in 10–15%; and 1–2% due to rare monogenic mutations in cardiac ion channels or associated proteins.[4]
  • Brugada Syndrome may account for up to 50% of all [[SCD]s in young individuals without structural heart disease. [5]
  • The prevalence of nonsustained VT detected by 24-hour Ambulatory ECGs was 4% in 98 elderly, disease-free individuals in the Baltimore Longitudinal Study of Aging,[6] 4% in 106 active elderly people,[7] 2% in 50 elderly people without cardiovascular disease,[8] 4% in 729 elderly women and 13% in 643 elderly men in the Cardiovascular Health Study,[9] 3% in 135 elderly men and 2% in 297 elderly women without cardiovascular disease,[10] 9% in 385 elderly men and 8% in 806 elderly women with hypertension, valvular disease, or cardiomyopathy,[10] 6% in 395 elderly men and 15% in 771 elderly women with coronary artery disease (CAD),[10] and 5% in a well population of 80 year olds in the Bronx Longitudinal Aging Study.[11]
  • The prevalence of complex ventricular arrhythmia in elderly people in these studies was 50%,5 31%,6 20%,7 16% in women and 28% in men,[10] 31% in men and 30% in women without cardiovascular disease,[10] 54% in men and 55% in women with hypertension, valvular disease, or cardiomyopathy,[10] and 69% in men and 68% in women with CAD.[10]
  1. ↑ Stevenson WG (2009). "Ventricular scars and ventricular tachycardia". Trans Am Clin Climatol Assoc. 120: 403–12. PMC 2744510. PMID 19768192.
  2. ↑ Gupta AK, Thakur RK (2001). "Wide QRS complex tachycardias". Med Clin North Am. 85 (2): 245–66, ix–x. PMID 11233948.
  3. ↑ Issa Z, Miller JM, Zipes DP(2009). Approach to Wide QRS Complex Tachycardias. Arrhythmology and Electrophysiology: A Companion to Braunwald's heart disease (1st ed., pp. 393). Philadelphia, Pa: Saunders Elsevier.
  4. ↑ Zipes DP, Jalife J(2009). Cardiac electrophysiology: from cell to bedside (5th ed.). Philadelphia, Pa: Saunders Elsevier.
  5. ↑ Zipes DP, Jalife J(2009). Cardiac electrophysiology: from cell to bedside (5th ed.). Philadelphia, Pa: Saunders Elsevier.
  6. ↑ Fleg JL, Kennedy HL (1982). "Cardiac arrhythmias in a healthy elderly population: detection by 24-hour ambulatory electrocardiography". Chest. 81 (3): 302–7. PMID 7056104.
  7. ↑ Camm AJ, Evans KE, Ward DE, Martin A (1980). "The rhythm of the heart in active elderly subjects". Am Heart J. 99 (5): 598–603. PMID 7369099.
  8. ↑ Kantelip JP, Sage E, Duchene-Marullaz P (1986). "Findings on ambulatory electrocardiographic monitoring in subjects older than 80 years". Am J Cardiol. 57 (6): 398–401. PMID 3946253.
  9. ↑ Manolio TA, Furberg CD, Rautaharju PM, Siscovick D, Newman AB, Borhani NO; et al. (1994). "Cardiac arrhythmias on 24-h ambulatory electrocardiography in older women and men: the Cardiovascular Health Study". J Am Coll Cardiol. 23 (4): 916–25. PMID 8106697.
  10. ↑ 10.0 10.1 10.2 10.3 10.4 10.5 10.6 Aronow WS, Ahn C, Mercando AD, Epstein S, Kronzon I (2002). "Prevalence and association of ventricular tachycardia and complex ventricular arrhythmias with new coronary events in older men and women with and without cardiovascular disease". J Gerontol A Biol Sci Med Sci. 57 (3): M178–80. PMID 11867655.
  11. ↑ Frishman WH, Sokol S, Aronson MK, Wassertheil-Smoller S, Katzman R (1998). "Risk factors for cardiovascular and cerebrovascular diseases and dementia in the elderly". Curr Probl Cardiol. 23 (1): 1–62. PMID 9494777.
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