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'''Transitional cell carcinoma''' is a type of [[cancer]] that originates in the [[kidney]], [[bladder]] or [[ureter]]. It is the most common type of [[bladder cancer]]. It arises from the [[transitional epithelium]] lining found in these organs.
'''Transitional cell carcinoma''' is a type of [[cancer]] that originates in the [[kidney]], [[bladder]] or [[ureter]]. It is the most common type of [[bladder cancer]]. It arises from the [[transitional epithelium]] lining found in these organs.
==Classification==
Based on the growth pattern, transitional cell [[carcinoma]] may be classified into either papillary urothelial carcinoma or non-papillary urothelial carcinoma. Transitional cell carcinoma may be classified according to [[World Health Organization]] in a collaborative effort conjointly with the International Society of Urological Pathologists (ISUP) into two groups: infiltrating urothelial carcinomas and non-invasive urothelial carcinomas.<ref name="pmid12461053">{{cite journal| author=Oosterhuis JW, Schapers RF, Janssen-Heijnen ML, Pauwels RP, Newling DW, ten Kate F| title=Histological grading of papillary urothelial carcinoma of the bladder: prognostic value of the 1998 WHO/ISUP classification system and comparison with conventional grading systems. | journal=J Clin Pathol | year= 2002 | volume= 55 | issue= 12 | pages= 900-5 | pmid=12461053 | doi= | pmc=PMC1769816 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12461053  }} </ref> Based on the degree of [[cellular differentiation]], transitional cell carcinoma may be classified into two grades: low grade and high grade.


==References==
==References==

Revision as of 13:39, 24 February 2016

Transitional cell carcinoma Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Transitional cell carcinoma is a type of cancer that originates in the kidney, bladder or ureter. It is the most common type of bladder cancer. It arises from the transitional epithelium lining found in these organs.

Classification

Based on the growth pattern, transitional cell carcinoma may be classified into either papillary urothelial carcinoma or non-papillary urothelial carcinoma. Transitional cell carcinoma may be classified according to World Health Organization in a collaborative effort conjointly with the International Society of Urological Pathologists (ISUP) into two groups: infiltrating urothelial carcinomas and non-invasive urothelial carcinomas.[1] Based on the degree of cellular differentiation, transitional cell carcinoma may be classified into two grades: low grade and high grade.


References

  1. Oosterhuis JW, Schapers RF, Janssen-Heijnen ML, Pauwels RP, Newling DW, ten Kate F (2002). "Histological grading of papillary urothelial carcinoma of the bladder: prognostic value of the 1998 WHO/ISUP classification system and comparison with conventional grading systems". J Clin Pathol. 55 (12): 900–5. PMC 1769816. PMID 12461053.

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