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{{Transitional cell carcinoma}}
{{Transitional cell carcinoma}}
{{CMG}}
{{CMG}};{{AE}} {{PSK}}
==Overview==
==Overview==
MRI findings of transitional cell carcinoma of renal pelvis include isointense to renal parenchyma on T1 and T2, moderate enhancement on T1 contrast. MRI findings of transitional cell carcinoma of bladder and ureter include isotense to muscle on T1 signal, slightly hyperintense to muscle on T2 signal, and demonstrate enhancement on contrast MRI.
==MRI==
==MRI==
===Transitional cell carcinoma of bladder===
* MRI is superior to other modalities in locally staging the [[tumor]] and is in some instances able to distinguish T1 from T2 tumors on T2 weighted image.<ref name=radiopaedia>Transitional cell carcinoma of the bladder. Dr Ian Bickle and Dr Frank Gaillard et al. Radiopaedia.org 2015.http://radiopaedia.org/articles/transitional-cell-carcinoma-of-the-bladder Accessed on February, 18 2015</ref>
:* T1: isointense compared to [[muscle]]
:* T2: slightly hyperintense compared to muscle
:* T1 weighted image with gadolinium contrast: demonstrates enhancement


===Transitional cell carcinoma of the renal pelvis===
* MRI is as reliable as CT for staging of invasive or locally advanced disease and may be better at evaluating tumors at the base and dome of the bladder.
*Transitional cell carcinomas are isointense to renal parenchyma on both T1 and T2 weighted images. Following administration of Gadolinium, TCCs enhance but less so than normal renal parenchyma.
*T1 : Isointense to renal parenchyma
*Moderate enhancement on gadolinium


* Gadolinium-enhanced MRI may be superior to CT to detect superficial and multiple tumors, extravesical tumor extension, and surrounding organ invasion.<ref name="pmid15615961">{{cite journal| author=Tekes A, Kamel I, Imam K, Szarf G, Schoenberg M, Nasir K et al.| title=Dynamic MRI of bladder cancer: evaluation of staging accuracy. | journal=AJR Am J Roentgenol | year= 2005 | volume= 184 | issue= 1 | pages= 121-7 | pmid=15615961 | doi=10.2214/ajr.184.1.01840121 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15615961  }}</ref><ref name="pmid8090898">{{cite journal| author=Kim B, Semelka RC, Ascher SM, Chalpin DB, Carroll PR, Hricak H| title=Bladder tumor staging: comparison of contrast-enhanced CT, T1- and T2-weighted MR imaging, dynamic gadolinium-enhanced imaging, and late gadolinium-enhanced imaging. | journal=Radiology | year= 1994 | volume= 193 | issue= 1 | pages= 239-45 | pmid=8090898 | doi=10.1148/radiology.193.1.8090898 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8090898  }}</ref>
* MRI is useful for patients with contrast dye allergy
* . Findings on MRI diagnostic of transitional cell carcinoma include:<ref name="BrowneMeehan2005">{{cite journal|last1=Browne|first1=Ronan F. J.|last2=Meehan|first2=Conor P.|last3=Colville|first3=Jane|last4=Power|first4=Raymond|last5=Torreggiani|first5=William C.|title=Transitional Cell Carcinoma of the Upper Urinary Tract: Spectrum of Imaging Findings1|journal=RadioGraphics|volume=25|issue=6|year=2005|pages=1609–1627|issn=0271-5333|doi=10.1148/rg.256045517}}</ref>
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Isointense to muscle
T2 Signal
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Isointense to renal parenchyma
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Slightly hyperintense to muscle
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Slightly hyperintense to muscle
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T1 C+ (Gd):
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Moderate enhancement
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Enhancement
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*Sessile or nodular tumors
Enhancement
*They grow deeper into the layers of the wall of the renal pelvis or ureter rather than into its cavity
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[[Category:Disease]]
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]

Latest revision as of 16:16, 23 July 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]

Overview

MRI findings of transitional cell carcinoma of renal pelvis include isointense to renal parenchyma on T1 and T2, moderate enhancement on T1 contrast. MRI findings of transitional cell carcinoma of bladder and ureter include isotense to muscle on T1 signal, slightly hyperintense to muscle on T2 signal, and demonstrate enhancement on contrast MRI.

MRI

  • MRI is as reliable as CT for staging of invasive or locally advanced disease and may be better at evaluating tumors at the base and dome of the bladder.
  • Gadolinium-enhanced MRI may be superior to CT to detect superficial and multiple tumors, extravesical tumor extension, and surrounding organ invasion.[1][2]
  • MRI is useful for patients with contrast dye allergy
  • . Findings on MRI diagnostic of transitional cell carcinoma include:[3]
Signal Renal Pelvis Ureter Urinary Bladder

T1 Signal

Isointense to renal parenchyma

Isointense to muscle

Isointense to muscle

T2 Signal

Isointense to renal parenchyma

Slightly hyperintense to muscle

Slightly hyperintense to muscle

T1 C+ (Gd):

Moderate enhancement

Enhancement

Enhancement

References

  1. Tekes A, Kamel I, Imam K, Szarf G, Schoenberg M, Nasir K; et al. (2005). "Dynamic MRI of bladder cancer: evaluation of staging accuracy". AJR Am J Roentgenol. 184 (1): 121–7. doi:10.2214/ajr.184.1.01840121. PMID 15615961.
  2. Kim B, Semelka RC, Ascher SM, Chalpin DB, Carroll PR, Hricak H (1994). "Bladder tumor staging: comparison of contrast-enhanced CT, T1- and T2-weighted MR imaging, dynamic gadolinium-enhanced imaging, and late gadolinium-enhanced imaging". Radiology. 193 (1): 239–45. doi:10.1148/radiology.193.1.8090898. PMID 8090898.
  3. Browne, Ronan F. J.; Meehan, Conor P.; Colville, Jane; Power, Raymond; Torreggiani, William C. (2005). "Transitional Cell Carcinoma of the Upper Urinary Tract: Spectrum of Imaging Findings1". RadioGraphics. 25 (6): 1609–1627. doi:10.1148/rg.256045517. ISSN 0271-5333.

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